Common carrier Cofactor / common carrier unreviewed
NADP+
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Pathways
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Categories
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As substrate
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As product
Reactions involving NADP+
Every recorded step where this molecule takes part
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GSSG + NADPH + H+ -> 2 GSH + NADP+
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produced Heme oxygenase (HO-1 inducible; HO-2 constitutive) Heme Degradation (Bilirubin Pathway) ST-0185 rate-limiting
Heme + O₂ + NADPH + H⁺ → biliverdin IXα + Fe²⁺/³⁺ + CO + NADP⁺ + H₂O
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Biliverdin IXα + NADPH + H⁺ → bilirubin IXα + NADP⁺
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Dihydrofolate (DHF) + NADPH + H⁺ → tetrahydrofolate (THF) + NADP⁺
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5,10-Methylene-THF + NADPH + H⁺ → 5-methyl-THF + NADP⁺
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Drug + O2 + NADPH -> hydroxylated/oxidized drug + H2O + NADP+
Recent literature
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