HMG-CoA
Reactions involving HMG-CoA
Every recorded step where this molecule takes part
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HMG-CoA + 2 NADPH + 2 H+ → mevalonate + 2 NADP+ + CoA-SH
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HMG-CoA → acetoacetate + acetyl-CoA
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Acetoacetyl-CoA + acetyl-CoA + H2O → HMG-CoA + CoA-SH
Showing all 3 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Cholesterol Biosynthesis (Mevalonate Pathwa… | → | Ketogenesis | within category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Systematic enzyme and cofactor engineering for efficient ursolic acid biosynthesis in <i>Yarrowia lipolytica</i>.
Elsharawy H, He Q, Zeng W, Zhou J. · 2026-07-17
open access unreviewed -
2
Enhancing myrcene biosynthesis in yeast through nuclear compartmentalization.
Wang Z, Wang J, Liu Y, Chen M, Lu X, Xia Y, Xiao S, Tang H, Yang X, He Y. · 2026-06-27
open access unreviewed -
3
Altered Acylcarnitine Metabolism in cardiac diseases: From molecular mechanisms to translational potential.
Wu J, Zhang Y, Liu J, Zhao W, Liu X, Dan J. · 2026-09-25
open access unreviewed -
4
Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort).
Pongsittisak W, Phannajit J, Kittanamongkolchai W, Tangwonglert T, Chanchairujira T, Kiattisunthorn K, Varees… · 2026-10-04
open access unreviewed -
5
Clinical considerations on the use of evinacumab for the treatment of homozygous familial hypercholesterolemia.
Bajaj A, McGuire M, Shugg S, Godin R, Underberg JA. · 2026-08-11
open access unreviewed -
6
Plant essential oils against woody plant fungal pathogens: chemical composition, antifungal mechanisms, and translational challenges.
Alizadeh M. · 2026-09-18
open access unreviewed -
7
Impaired Glur2 palmitoylation in cerebellar Purkinje cells of a Friedreich ataxia mouse model.
Mercado-Ayón E, Coulman J, Lee JY, Lancaster E, Goga E, Asad M, Witze E, Lynch DR. · 2026-08-09
unreviewed -
8
VA-ECMO and HIET for toxic cardiogenic shock in an elderly patient following severe poly-intoxication: A case report.
Ouwerkerk JJJ, Poublon NA, Westra AF, Kraaijvanger N. · 2026-07-04
open access unreviewed -
9
Inflammation and carcinogenesis: molecular targets and small-molecule intervention strategies.
Lu WJ, Ojha R, Rana M, Gautam V, Li JY, Wang SA. · 2026-06-26
open access unreviewed -
10
<i>De novo</i> production of (-)-limonene, (-)-carveol and (-)-carvone via engineering <i>Rhodotorula toruloides</i>.
Dong Y, Cui S, Du B, Zhang X, Hou J, Lin X, Qin Y, Wang X, Yang X. · 2026-06-13
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.