HMG-CoA
Reactions involving HMG-CoA
Every recorded step where this molecule takes part
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HMG-CoA + 2 NADPH + 2 H+ → mevalonate + 2 NADP+ + CoA-SH
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HMG-CoA → acetoacetate + acetyl-CoA
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Acetoacetyl-CoA + acetyl-CoA + H2O → HMG-CoA + CoA-SH
Showing all 3 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Cholesterol Biosynthesis (Mevalonate Pathwa… | → | Ketogenesis | within category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
<i>De novo</i> production of (-)-limonene, (-)-carveol and (-)-carvone via engineering <i>Rhodotorula toruloides</i>.
Dong Y, Cui S, Du B, Zhang X, Hou J, Lin X, Qin Y, Wang X, Yang X. · 2026-06-13
open access unreviewed -
2
A cell-free system for 1,6-hexanediamine synthesis using bulk chemical caprolactam as the feedstock.
Liu R, Li C, Zhang Y, Li G, Deng Y. · 2026-06-05
open access unreviewed -
3
Biological-chemical method for synthesizing <i>p</i>-menthane-3,8-diol.
Zuo X, Zhang H, Zhang Z, Ma Y, Zhang C, Lu W. · 2026-05-12
open access unreviewed -
4
Olivetol induces a non-genotoxic nucleolar DNA damage response via membrane-dependent stress signaling.
Deriglazov DA, Petrova NV, Luzhin AV, Pavlenko NG, Tatarskiy VV, Kazakov EP, Kireev II, Kurkin AV, Novoselov … · 2026-05-18
open access unreviewed -
5
Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.
Tayebi SM, Mirzaei M, Stout JR. · 2026-05-05
open access unreviewed -
6
Constructing an efficient synthesis pathway in peroxisomes to boost <i>β</i>-myrcene production in yeast.
Chang J, Wang J, Dong T, Shu Y, Wang Y, Xiao W, Yao M, Yuan Y. · 2026-04-25
open access unreviewed -
7
A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals.
Mahony C, Bartlett A, Fitzpatrick S, Galli C, Hunt P, Inselman A, Jimenez J, Krzykwa J, Larson J, Rider C, Ro… · 2026-04-28
open access unreviewed -
8
Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>.
Xu C, Zhang W, Zhao Q, Lin X, Wang K, Wang M, Tan T. · 2026-04-15
open access unreviewed -
9
Synergistic engineering of monoterpenoid synthase and metabolic pathways to enhance α-terpineol production in <i>Saccharomyces cerevisiae</i>.
Wang S, Wang X, Wang Y, Li C. · 2026-04-10
open access unreviewed -
10
Emerging roles of ATP citrate lyase in kidney diseases: from pathogenic driver to therapeutic target.
Wei M, Tao M, Tan H, Jin Z, Yang Y, Xiao Z, Li G, Chen Y. · 2026-04-09
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.