Formylglycinamide ribonucleotide (FGAR)
Reactions involving Formylglycinamide ribonucleotide (FGAR)
Every recorded step where this molecule takes part
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FGAR → formylglycinamidine ribonucleotide (FGAM)
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10-Formyl-THF + glycinamide ribonucleotide (GAR) → formyl-GAR + THF
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GAR → formylglycinamide ribonucleotide (FGAR)
Showing all 3 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| One-Carbon Metabolism (Folate Cycle) | → | Purine De Novo Synthesis (IMP synthesis thr… | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Oncolytic virus hijacks GOT1 and pyrimidinosomes to fuel pyrimidine synthesis for replication in tumor cells.
Tang N, Gong Y, Zhao C, Niu Y, Tan L, Song C, Qiu X, Liao Y, Yu S, Ding C, Lin S, Sun Y. · 2026-04-09
open access unreviewed -
2
Hypoxia-driven microRNA-27b underlies pathologic cardiac endoreplication in heart disease.
Mirtschink P, Yuan T, Bischof C, Pham MD, Zhu C, Ware A, Mao Y, Wu M, Rogg EM, Bottermann K, Gonzalez-Gonoggi… · 2026-05-14
open access unreviewed -
3
Click Reactions in Kinetic Target-Guided Synthesis: Progress in the Discovery of Inhibitors for Biological Targets.
Parvatkar PT, Satam N. · 2026-04-01
open access unreviewed -
4
Structural insights into substrate binding, domain swapping and heat resistance of a hyperthermostable archaeal AIR synthetase.
Chen YH, Huang YC, Rao RGR, Chang HC, Lan YH, Nakagawa A, Jeyaraman J, Chen CJ. · 2026-01-23
unreviewed -
5
Recent insights into the roles and therapeutic potentials of GLS1 in inflammatory diseases.
Sheng JX, Liu YJ, Yu J, Wang R, Chen RY, Shi JJ, Yang GJ, Chen J. · 2025-04-02
cited 1× open access unreviewed -
6
One-Carbon Metabolism and Midbrain Dopaminergic Cells in Lesch-Nyhan Disease.
Alsuwaidi S, Ernst C. · 2025-11-07
open access unreviewed -
7
Metabolic profiling reveals channeled de novo pyrimidine and purine biosynthesis fueled by mitochondrially generated aspartic acid in cancer cells.
Pareek V, Benkovic S. · 2025-10-08
cited 3× open access unreviewed -
8
Cellular view of metabolism: metabolic biomolecular condensates.
Saldivar EV, Field S, Rhee SY. · 2025-08-22
cited 1× open access unreviewed -
9
Phase Separation Regulates Metabolism, Mitochondria, and Diseases.
Gao C, Ding P, Zhang C, Gao J. · 2025-07-01
open access unreviewed -
10
A high throughput assay for phosphoribosylformylglycinamidine synthase.
Sharma N, Otsuka Y, Scampavia L, Spicer TP, French JB. · 2025-01-15
cited 2× open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.