AICAR
Reactions involving AICAR
Every recorded step where this molecule takes part
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10-Formyl-THF + AICAR → formyl-AICAR + THF
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AICAR → 5-formamidoimidazole-4-carboxamide ribonucleotide (FAICAR)
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SAICAR → 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR)
Showing all 3 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Purine De Novo Synthesis (IMP synthesis thr… | → | One-Carbon Metabolism (Folate Cycle) | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Interpol review of forensic drug chemistry, 2022-2025.
Love D, Page E. · 2026-08-16
open access unreviewed -
2
Targeting ROAM1 with UDP-GlcNAc nanosheets selective activates lysosomal AMPK to resolve metabolic dysfunction-associated steatotic liver disease.
Zhu J, Sun T, Wei F, Wang D, Liu F, Chen D, Liu X, Wang C, Deng S, Yang Y, Xiong Y, Xiang H, Li J, Li S, Ma W… · 2026-07-12
open access unreviewed -
3
Enhanced production of l-histidine in <i>Escherichia coli</i> through systematic metabolic engineering and CER controlled fermentation.
Zhang B, Liu X, Zhao T, Hao J, Wang Z, Xia M, Chen N, Wang X, Fan X. · 2026-05-25
open access unreviewed -
4
PLIN3-triggered lipophagic flux releases FFAs to facilitate CSFV propagation.
Li B, Zou L, Sun C, Jiang J, Li S, Wang J, He Y, Qin Y, Zeng S, Song Y, Zeng W, Yi L, Fan S, Chen J, Wu K. · 2026-02-25
cited 1× open access unreviewed -
5
Targeting mitochondrial quality control in diabetic kidney disease: emerging therapeutic opportunities.
Luo J, Lu F, Cuciureanu M, Xu X, Dong H, Gong M. · 2026-02-03
cited 2× open access unreviewed -
6
Investigation of exercise-mimetic bioactive molecules as modulators of MMP activity and expression in cancer cells.
Vo HVT, Patton GN, Park JS, Kim SJ, Kim N, Lee HJ. · 2026-01-19
cited 3× open access unreviewed -
7
AMPK‐Mediated Lipid Metabolic Reprogramming in Cancer: From Mechanisms to Targeted Therapies
Chen Y, Liu W, Luo B. · 2026-10-01
open access unreviewed -
8
Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities.
Yang S, Li R, Yu C, Li J, Zhou X. · 2026-10-04
open access unreviewed -
9
Caffeic acid phenethyl ester inhibits adipogenic differentiation in association with INSR suppression and AMPK activation.
Zhang YM, Liang LC, Ma CH, Liang SC, Xue W. · 2026-10-02
unreviewed -
10
Vascular calcification: pathogenic mechanisms, signaling crosstalk and translational therapeutics.
Hua R, Qiao B, Liu X, Jiang B, Wu J, Zhang C, Liu H, Wang B, Wei S, Chen Y. · 2026-10-02
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.