Junction / hub Pathway metabolite unreviewed

Serine

Pathways

Reactions involving Serine

Every recorded step where this molecule takes part

All 3 Consumed 3 Produced 0

consumed Serine palmitoyltransferase (SPT) Sphingolipid Synthesis ST-0324 rate-limiting

Serine + palmitoyl-CoA -> 3-ketosphinganine + CO2 + CoA-SH
consumed Cystathionine beta-synthase (CBS) Methionine Cycle / Transmethylation (SAM … ST-0175 rate-limiting

Homocysteine + L-serine → cystathionine + H₂O
consumed Serine hydroxymethyltransferase (SHMT1/SHMT2) One-Carbon Metabolism (Folate Cycle) ST-0161

L-serine + THF ⇌ glycine + 5,10-methylene-THF + H₂O

Showing all 3 reactions.

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