Junction / hub Pathway metabolite unreviewed

Acetoacetate

Pathways

Reactions involving Acetoacetate

Every recorded step where this molecule takes part

All 7 Consumed 3 Produced 4

consumed D-beta-hydroxybutyrate dehydrogenase (BDH1) Ketogenesis ST-0085

Acetoacetate + NADH + H+ ⇌ D-β-hydroxybutyrate + NAD+
consumed Non-enzymatic (spontaneous decarboxylation) Ketogenesis ST-0086

Acetoacetate → acetone + CO2
consumed Succinyl-CoA:3-ketoacid CoA transferase (SCOT / OXCT1) Ketolysis (Ketone Body Utilization) ST-0088

Acetoacetate + succinyl-CoA → acetoacetyl-CoA + succinate

Showing all 3 reactions.

Produced in one pathway, consumed in another

4 links

Produced in		Consumed in	Link
Amino Acid Catabolism Overview (glucogenic …	→	Ketogenesis	cross-category
Amino Acid Catabolism Overview (glucogenic …	→	Ketolysis (Ketone Body Utilization)	cross-category
Ketogenesis	→	Ketolysis (Ketone Body Utilization)	within category
Ketolysis (Ketone Body Utilization)	→	Ketogenesis	within category

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