Unconjugated bilirubin
Reactions involving Unconjugated bilirubin
Every recorded step where this molecule takes part
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consumed OATP1B1/OATP1B3 uptake + ligandin binding (transport, not enzymatic) Heme Degradation (Bilirubin Pathway) ST-0187
Unconjugated bilirubin (albumin-bound) → hepatocyte-associated unconjugated bilirubin
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produced Bacterial beta-glucuronidases + reductases (gut microbiota) Heme Degradation (Bilirubin Pathway) ST-0189
Conjugated bilirubin → unconjugated bilirubin → urobilinogen
Showing all 2 reactions.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Analytical and clinical validation of a competitive ELISA for serum indoxyl sulfate and its clinical association with chronic kidney disease risk stratification.
Hou YC, Chuang YC, Cheng YW, Huang HY, Chen LY, Tseng TL, Lu KC. · 2026-06-02
open access unreviewed -
2
Regulation of Diverse Endogenous Metabolic and Signaling Pathways by UDP-Glucuronosyltransferases (UGTs) Revealed by Metabolomics of Knockout Mice.
Falah K, Liu J, Nguyen N, Chen S, Tukey RH, Nigam SK. · 2026-08-15
open access unreviewed -
3
Bilirubin and the Yellow Players in Ferroptosis: A Delicate Balance in Human Health and Disease, with a Focus on the Liver, Cardiovascular System, and Brain.
Dalla Verde C, Vitek L, Tiribelli C, Gazzin S. · 2026-09-21
open access unreviewed -
4
Evaluation of Liver Biomarker Levels in Farmers Occupationally Exposed to Pesticides: A Cross-Sectional Study.
Dang HT, Nguyen TP, Pham TTY, Luu CT, Nguyen HTT, Nguyen OTK, Ngo OTP, Do CTT, Bui HTN, Duong QH. · 2026-09-14
open access unreviewed -
5
Bilirubin impacts microglial lipophagy via the AMPK-mTOR signaling pathway.
Liu S, Li L, Li J, Li S, Chen J, Sun Q, Zhang Y, Hua Z. · 2026-09-21
unreviewed -
6
Natural Bioactive Compounds in Rheumatoid Arthritis: Experimental Evidence from Adjuvant Arthritis Model Supporting Combination Strategies with Methotrexate.
Umar M, Ahmad W, Bauerova K. · 2026-09-07
open access unreviewed -
7
DAT-negative autoimmune hemolytic anemia following acute hepatitis a in a pediatric patient with elevated IgA: a rare case report and literature review.
Alfirzly H, Abou Deb G, Abdullah C. · 2026-08-04
open access unreviewed -
8
Silent acute STEMI associated with alcohol withdrawal in a 46-year-old male: a case report.
Jha A, Adhikari S, Poudel S, Niraula O, Dhungana D, Dhillon I. · 2026-08-12
open access unreviewed -
9
Cochlear implantation for sensorineural hearing loss caused by neonatal hyperbilirubinemia.
Cheng MY, Oghalai JS. · 2026-09-01
unreviewed -
10
Liver response to early embryonic stimulation with xylo-and mannooligosaccharides in broiler chickens.
Bełdowska A, Barszcz M, Tuśnio A, Konopka A, Gawin K, Święch E, Siwek M, Dunisławska A. · 2026-05-28
open access unreviewed
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