Ubiquinol (CoQH2)
Reactions involving Ubiquinol (CoQH2)
Every recorded step where this molecule takes part
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consumed Complex III (ubiquinol:cytochrome c oxidoreductase; cytochrome bc1) Electron Transport Chain (Complexes I–IV) ST-0279
QH2 + 2 cytochrome c(Fe3+) + 2 H+matrix → Q + 2 cytochrome c(Fe2+) + 4 H+intermembrane space
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produced Complex I (NADH:ubiquinone oxidoreductase) Electron Transport Chain (Complexes I–IV) ST-0277
NADH + H+ + ubiquinone (Q) → NAD+ + ubiquinol (QH2)
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Succinate + Q → fumarate + QH2
Showing all 3 reactions.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Imbalance of mitochondria and abnormalities in lipid metabolism in Diabetic Tubulopathy.
Sun C, Li Y, Tao Y, Wu Q, Liu B, Zhou Y. · 2026-01-18
open access unreviewed -
2
Ferroptosis and prostate cancer: A translational path from molecular mechanisms to precision therapy.
Huang Y, Ma Y, He J, Song T. · 2025-12-08
open access unreviewed -
3
Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress.
Ndoci M, Bhattacharya S, Agrawal I, Hinze Y, Lemke K, Schumacher AL, Uijttewaal E, Elling U, Lawo S, Giavalis… · 2026-06-08
cited 1× open access unreviewed -
4
DHODH-Mediated Suppression of Ferroptosis Supports Radioresistance and Represents a Therapeutic Vulnerability in Lung Cancer.
Mao C, Wu S, Rajacharya GH, Wang M, Lu Z, Huo D, Yan Y, Chen X, Lei G, Xu Z, Li Q, Sun M, Zhao X, Zhuang L, J… · 2026-07-01
unreviewed -
5
Metal-organic framework-based fuel-driven chemical reaction network for ferroptosis therapy.
Guo D, Lin Q, Jin Q, Zhang L, Liu N, Jiang M, Peng S, Xu J, Gao X, Zong L, Zhu X. · 2026-06-29
unreviewed -
6
The Dual Role of Ferroptosis in Cancer: Molecular Mechanisms, Microenvironment Crosstalk, and Precision Therapeutics.
Zhu Y, Chen M, Chen J, Wang J, Zhou R, Cui Y, Li G. · 2026-06-03
open access unreviewed -
7
PRMT5 inhibition sensitizes B-cell lymphoma cells to ferroptosis.
Liu Y, Chen R, Gao X, Zhu F, Ni Q, Bates PD, Wu S, Zai Z, Obernberger VA, Weerawardhene K, Tourdot TK, Petta … · 2026-04-17
open access unreviewed -
8
Research Progress on the Role of Traditional Chinese Medicine in Regulating Ferroptosis in Cardiovascular Diseases.
Li P, Qi ZM, Li SC, Liang JL, Xu TY, Yu P. · 2026-05-23
open access unreviewed -
9
Tipping the balance: NRF2's dual role in ferroptotic fate.
de Souza I, da Silva Teixeira AB, Ferreira Dos Santos A, Friedmann Angeli JP, Ribeiro Reily Rocha C. · 2026-05-30
open access unreviewed -
10
Oxidative Stress-Related Programmed Cell Death in Male Infertility: Focussing on Ferroptosis.
Sanei-Ataabadi N, Aboutalebi F, Dormiani K, Nasr-Esfahani MH. · 2026-05-01
open access unreviewed
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