Ubiquinol (CoQH2)
Reactions involving Ubiquinol (CoQH2)
Every recorded step where this molecule takes part
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consumed Complex III (ubiquinol:cytochrome c oxidoreductase; cytochrome bc1) Electron Transport Chain (Complexes I–IV) ST-0279
QH2 + 2 cytochrome c(Fe3+) + 2 H+matrix → Q + 2 cytochrome c(Fe2+) + 4 H+intermembrane space
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produced Complex I (NADH:ubiquinone oxidoreductase) Electron Transport Chain (Complexes I–IV) ST-0277
NADH + H+ + ubiquinone (Q) → NAD+ + ubiquinol (QH2)
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Succinate + Q → fumarate + QH2
Showing all 3 reactions.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Imbalance of mitochondria and abnormalities in lipid metabolism in Diabetic Tubulopathy.
Sun C, Li Y, Tao Y, Wu Q, Liu B, Zhou Y. · 2026-01-18
cited 3× open access unreviewed -
2
Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review).
Feng X, Zhang J, Ma Q, Sun C. · 2026-08-28
open access unreviewed -
3
Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review).
Li J, Liu A, Gao W, Xing L, Duan P, Li H. · 2026-08-21
open access unreviewed -
4
The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy.
Di Paola A, Marrapodi MM, Di Feo G, Di Martino M, Di Pinto D, Argenziano L, Di Domenico O, Rossi F, Pota E. · 2026-09-10
open access unreviewed -
5
Experimental workflows for the accurate identification of mitochondrial redox events.
Hernansanz-Agustín P, Bolaños JP, Borrás C, Cabiscol E, Campuzano V, de Cubas L, Enríquez JA, Fabregat I, Gon… · 2026-09-09
open access unreviewed -
6
Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC.
Saatci O, Ulukan B, Cetin M, Kuasne H, Martinez C, Percin E, Oleinik N, Savoca MT, Nehme A, Hernández-Corchad… · 2026-08-31
cited 1× open access unreviewed -
7
Ferroptosis: Newly Emerged Regulator for Human Disease.
Xiao D, Ye L, Jiang T, Liu M, Zhou Y. · 2026-08-19
cited 1× open access unreviewed -
8
Ferroptosis in skeletal muscle: from molecular mechanisms to therapeutic interventions.
Ren K, An Y, Zhou K, Cheng X, Meng T, Li C, Xu H, Zhang P, Xu Y. · 2026-08-02
open access unreviewed -
9
DHODH Drives Sunitinib Resistance Via a Non-Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC.
Qian S, Pu S, Xu Z, Ding Y, Jin L, Li B, Li Q, Xi X, Wang Z, Xing J, Xu A. · 2026-06-23
cited 1× open access unreviewed -
10
Ferroptosis and prostate cancer: A translational path from molecular mechanisms to precision therapy.
Huang Y, Ma Y, He J, Song T. · 2025-12-08
cited 1× open access unreviewed
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