S-adenosylhomocysteine
Reactions involving S-adenosylhomocysteine
Every recorded step where this molecule takes part
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SAH + H₂O ⇌ homocysteine + adenosine
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produced Phosphatidylethanolamine N-methyltransferase (PEMT) Phospholipid Synthesis (Kennedy / CDP pat… ST-0310
Phosphatidylethanolamine + 3 SAM -> phosphatidylcholine + 3 SAH
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Norepinephrine + SAM -> epinephrine + SAH
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Substrate + SAM -> methylated metabolite + SAH
Showing all 4 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Catecholamine Synthesis | → | Methionine Cycle / Transmethylation (SAM Cy… | within category |
| Phase II - Conjugation | → | Methionine Cycle / Transmethylation (SAM Cy… | cross-category |
| Phospholipid Synthesis (Kennedy / CDP pathw… | → | Methionine Cycle / Transmethylation (SAM Cy… | cross-category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
A universal consuming endogenous H<sub>2</sub>S strategy using bismuth-metal-organic nanocapsule networks for overcoming osteosarcoma cisplatin resistance.
Lin Y, Yuan K, Liu Y, Du Y, Chang H, Hou L, Liang Y, Huang K, Yang S, Tang T. · 2026-08-18
open access unreviewed -
2
Hepatic methionine-cycle dysregulation is associated with immune-inflammatory and fibrogenic remodeling in biliary atresia.
Lv C, Dai X, Wang H, Gao X, Tan B, Yang C, Zhao Y, Zhang M. · 2026-08-15
unreviewed -
3
Homocysteine, cysteine and methionine are associated with 90-day prognosis in intracerebral hemorrhage patients.
Fang M, Xia T, Yin Y. · 2026-08-21
open access unreviewed -
4
Amino acid metabolic reprogramming by gut microbiota: a novel metabolic checkpoint in the tumor microenvironment.
Lin H, Deng X, Yang Y, Zhang R, Wang YD, Chen WD. · 2026-08-18
open access unreviewed -
5
Reconstituting a two-step pathway for <i>N</i>,<i>N</i>-dimethyltryptamine (DMT) biosynthesis in bacteria.
Junges LH, Pontes FLD, Mota FJT, Passaglia Bruschi G, Bonaldi MPF, de Souza EM, Müller-Santos M. · 2026-07-21
open access unreviewed -
6
Modulation of the response to immunotherapy in triple-negative breast cancer: the role of the microbiota and microbial metabolites in the tumor microenvironment.
Serrano-García L, Martínez-Salvador E, Belda-Marco A, Herrero-Oliva C, Cortés J, Llombart-Cussac A, Fernández… · 2026-07-08
open access unreviewed -
7
An integrated review of monkeypox: from pathogen and epidemiology to diagnostics, control, and challenges.
Li W, Yang Q, Xie W, Dong W, Chiu S. · 2026-07-06
open access unreviewed -
8
Metabolic engineering of <i>Vibrio natriegens</i> for the efficient biosynthesis of ergothioneine from sucrose using non-sterile fed-batch fermentation.
Liang X, Wang Y, Lv Y, Huang C, Huang Z, Wei J, Jiang S, Dong Z, Zhou Z, Lin M. · 2026-06-12
open access unreviewed -
9
Metabolic engineering of <i>Saccharomyces cerevisiae</i> for co-production of ergothioneine, salidroside and gadusol.
Zhang L, Xiao S, Wang D, Zhang P, Xu R, Hu L, Kang Z. · 2026-06-10
open access unreviewed -
10
Significance of GSH and H<sub>2</sub>S regulation for cancer: an intricate interplay between diet, microbiota, metabolic reprogramming, and immune health.
Majumder A, Majumder S, Bano S, Sen K, Nayak KB. · 2026-06-11
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.