S-adenosylhomocysteine
Reactions involving S-adenosylhomocysteine
Every recorded step where this molecule takes part
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SAH + H₂O ⇌ homocysteine + adenosine
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produced Phosphatidylethanolamine N-methyltransferase (PEMT) Phospholipid Synthesis (Kennedy / CDP pat… ST-0310
Phosphatidylethanolamine + 3 SAM -> phosphatidylcholine + 3 SAH
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Norepinephrine + SAM -> epinephrine + SAH
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Substrate + SAM -> methylated metabolite + SAH
Showing all 4 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Catecholamine Synthesis | → | Methionine Cycle / Transmethylation (SAM Cy… | within category |
| Phase II - Conjugation | → | Methionine Cycle / Transmethylation (SAM Cy… | cross-category |
| Phospholipid Synthesis (Kennedy / CDP pathw… | → | Methionine Cycle / Transmethylation (SAM Cy… | cross-category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Metabolic engineering of <i>Vibrio natriegens</i> for the efficient biosynthesis of ergothioneine from sucrose using non-sterile fed-batch fermentation.
Liang X, Wang Y, Lv Y, Huang C, Huang Z, Wei J, Jiang S, Dong Z, Zhou Z, Lin M. · 2026-06-12
open access unreviewed -
2
Metabolic engineering of <i>Saccharomyces cerevisiae</i> for co-production of ergothioneine, salidroside and gadusol.
Zhang L, Xiao S, Wang D, Zhang P, Xu R, Hu L, Kang Z. · 2026-06-10
open access unreviewed -
3
Significance of GSH and H<sub>2</sub>S regulation for cancer: an intricate interplay between diet, microbiota, metabolic reprogramming, and immune health.
Majumder A, Majumder S, Bano S, Sen K, Nayak KB. · 2026-06-11
open access unreviewed -
4
A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis.
Xie K, Jiang Y, Chen T, Liu S, Fang Y, Chen F, Shen J, Zeng X, Li P, Qiu T, Wang J, Yu L, Zang X, Wang N, Yua… · 2026-04-30
open access unreviewed -
5
Epigenetic regulators polyphenols in neurodegenerative diseases: a promising intervention strategy.
Li LH, Huang Y, Wang XX, Xu CC, Wu L, He KL, Han DX, Chang Z, Wang JQ, Ma RJ. · 2026-03-31
open access unreviewed -
6
HIV-1 Vpr activates microglia by upregulating m6A modification through ubiquitin-proteasome pathway-mediated degradation of the demethylase ALKBH5.
Peng Q, Li W, Qian F, Zhu Y, Hu S, Shi Y, Xia Y, Liu W, Shu X, Wan P, Liu Y, Sun B. · 2026-03-19
cited 2× open access unreviewed -
7
Interactions between nutrition and the epigenome: how can it be harnessed for public health?
Anastasopoulou M, Dereki I, Sgourou A, Lagoumintzis G. · 2026-03-12
open access unreviewed -
8
Autoinducer 2 as a universal language in microbial consortia: decoding molecular mechanisms, ecological impacts, and application.
Guo S, Mao B, Tang X, Zhang Q, Zhao J, Chen W, Cui S. · 2026-01-23
cited 2× open access unreviewed -
9
<i>Lactococcus lactis</i> subsp. Cremoris reprograms systemic metabolism and protects against myocardial injury.
Gacasan CA, Naudin CR, Weinberg J, Askew LC, Barbian ME, Jones DP, Jones RM. · 2026-01-04
cited 1× open access unreviewed -
10
L-serine dose-dependently ameliorates high-selenium-induced insulin resistance in mice.
Zhan S, Wang Q, Liu Y, Han F, Huang J, Li Z, Fan Q, Wu J, Huang Z. · 2026-05-30
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.