What it does, reaction by reaction
Methionine Cycle / Transmethylation (SAM Cycle, homocysteine) Amino Acid & Nitrogen Metabolism · Cytosol
SAH + H₂O ⇌ homocysteine + adenosine
Converts S-adenosylhomocysteine H2O into Homocysteine Adenosine
› Notes
S-adenosylhomocysteine hydrolase (AHCY) catalyzes a reversible reaction whose in vivo direction is driven toward hydrolysis by rapid removal of homocysteine and adenosine. SAH is a potent competitive inhibitor of many methyltransferases, so its clearance is necessary to preserve methylation potential.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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