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MS
Single-pathway Pathway metabolite unreviewed

SAICAR

0
Pathways
0
Categories
0
As substrate
0
As product

Reactions involving SAICAR

Every recorded step where this molecule takes part

Showing all 2 reactions.

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Chromatin dynamics and cellular energy homeostasis.

    Suganuma T, Workman JL. · 2026-10-01

    open access unreviewed
  2. 2
    Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase.

    E Silva IR, Mantovani M, Lino MESD, Albuquerque AO, da Silva JHM, Nagem RAP, Rojas AL, Sartori GR, Horjales E… · 2026-06-08

    open access unreviewed
  3. 3
    Adenosine Deaminase-Mediated Purine Dysfunction Leads to DNA Repair Inhibition and Senescence in Sporadic Amyotrophic Lateral Sclerosis.

    Hall B, Ebrahim YM, Sharpe JL, Makhija S, Ellis BCS, Wong KE, Walker H, Yagüe-Capilla M, Timmons HO, Bradley … · 2026-09-16

    open access unreviewed
  4. 4
    Distinct Urea Cycle Dysfunction Profiles Differentiate Acute Metabolic Decompensation in TMEM70 and MT-ATP6-Related Mitochondrial ATP Synthase Defects.

    Siri B, Martinelli D, Carrozzo R, Boenzi S, Cairoli S, Rizzo C, Giovanniello T, Häberle J, Dionisi-Vici C. · 2026-09-01

    cited 1× unreviewed
  5. 5
    Severe adenylosuccinate lyase deficiency with early autonomic dysfunction: functional characterization of a novel ADSL variant and exploratory treatment with disulfiram.

    Kravljanac R, Zikanova M, Milačić I, Tadić BV, Popović S, Oparnica V, Skopova V, Forejtova A, Baresova V. · 2026-06-15

    unreviewed
  6. 6
    PKM2: A gatekeeper in macrophage metabolic reprogramming.

    Li K, Wu M, Zhang Q, Wu J, Ding X, Xiao W. · 2026-01-28

    cited 2× open access unreviewed
  7. 7
    A novel homozygous variant causing fatal neonatal adenylosuccinate lyase (ADSL) deficiency presenting with respiratory failure and encephalopathy.

    Wolfe K, Armstrong L, Wambach C, Leon E, Ohrtman K, Miller I, Pyle T, Schroeder J, Fraser J, Kousa Y. · 2026-08-11

    open access unreviewed
  8. 8
  9. 9
  10. 10
    Nature Counts to Three: Universal Mg-Pinch Motif Polarizes the Cleaved Bond in NTP-Processing Enzymes.

    Dudas B, Berta D, Jambrina P, Buigues PJ, Suardiaz R, Gómez-Coca S, Deng W, Brooks BR, Vértessy BG, Rosta E. · 2026-07-13

    cited 1× open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.