What it does, reaction by reaction
1 reactions
Purine De Novo Synthesis (IMP synthesis through to AMP/GMP) Nucleotide Metabolism · Cytosol
step 8
Irreversible/directional
CAIR → succinylaminoimidazolecarboxamide ribonucleotide (SAICAR)
Converts Carboxyaminoimidazole ribonucleotide (CAIR) into SAICAR
› Notes
SAICAR synthetase catalyzes CAIR + aspartate + ATP → SAICAR + ADP + Pi. Aspartate donates N1 of the purine ring, while its carbon skeleton is later released as fumarate.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
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