Dihydroorotate

Europe PMC · from cache · sorted by publication date

1. 1
   Research progress of ferroptosis in gynecological diseases.

   Chen W, Zhou W, Liu S. · 2026-06-19

   open access unreviewed
2. 2
   PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators.

   Periyasamy S, Jarrett T, Truong J, Skouta R. · 2026-03-26

   open access unreviewed
3. 3
   FDA-approved IMPDH inhibitors synergize with ribavirin to inhibit respiratory syncytial virus by interfering with purine <i>de novo</i> synthesis.

   Hu H, Wang Q, Ai Q, Zhou P, He Y, Ye Z, Ma K, Zhou M, Huang S, Wang L, Qi N, Xiao G, Wang S. · 2026-03-17

   cited 2× open access unreviewed
4. 4
   Antitumor activity and structure-activity relationship of poly (ADP-ribose) polymerase (PARP)-based dual inhibitors.

   Yang C, Shang Y, Li X, Li J, Li H, Han J. · 2025-12-15

   open access unreviewed
5. 5
   Ubiquitination-dependent regulation of ferroptosis in ischemic heart and brain.

   Zhang YY, Long XY, Tian J, Luo XJ, Peng J. · 2026-06-08

   open access unreviewed
6. 6
   Ferroptosis and prostate cancer: A translational path from molecular mechanisms to precision therapy.

   Huang Y, Ma Y, He J, Song T. · 2025-12-08

   open access unreviewed
7. 7
   Contribution of dihydroorotate dehydrogenase complex to NADH supply and metabolic flux redirection in Clostridium acetobutylicum.

   Jiang D, Yi J, Zhu H, Gao L, Wang S, Liu G, Li L, Zhang Q, Wang M, Ehrenheich A, Li F, Xiao Y, Liu Z, Zhang K. · 2026-05-25

   unreviewed
8. 8
   Targeting dihydroorotate dehydrogenase (hDHODH) beyond the barrier: discovery of MEDS700 as blood-brain barrier permeable hDHODH inhibitor.

   Sainas S, Vigato C, Circosta P, Zonfrillo M, Servidei T, Alberti M, Rescigno M, Miggiano R, Gaidano V, Vitale… · 2026-04-27

   unreviewed
9. 9
   Novel noscapine derivative induces AML differentiation by dual-engaging DHODH and mitochondrial lipids to trigger a metabolic-epigenetic-transcriptional cascade.

   Shen S, Li D, Zhang Y, Li S, Li L, Shen W, Ma Y, Zhang W, Tao R, Wang W, Jiang B, Bai F, Liu C, Zhang Y, Yin … · 2026-05-22

   unreviewed
10. 10
    Dihydroorotate Dehydrogenase Inhibitors are Potent Antiviral Agents against Henipaviruses and Arenaviruses.

    Li Y, Ma J, Bott R, McMullan LK, Lo MK, Chatterjee P, Flint M, Spengler JR, Kunz KA, Argade MD, Ratia K, Rong… · 2026-08-11

    unreviewed

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