What it does, reaction by reaction
1 reactions
Pyrimidine De Novo Synthesis (through to UMP, then CTP/dTMP) Nucleotide Metabolism · Cytosol (one mitochondrial step)
step 3
Irreversible/directional
Carbamoyl aspartate → dihydroorotate
Converts Carbamoyl aspartate into Dihydroorotate
› Notes
Dihydroorotase catalyzes intramolecular cyclization/dehydration: carbamoyl aspartate ⇌ L-dihydroorotate + H2O. This zinc-dependent enzyme is the third CAD activity.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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