Alanine aminotransferase (ALT/GPT)
Cofactors used
What it does, reaction by reaction
Glucose-Alanine Cycle Carbohydrate Metabolism · Cytosol
Pyruvate + glutamate -> alanine + alpha-ketoglutarate (muscle)
Converts Pyruvate Glutamate into Alanine Alpha-ketoglutarate
› Notes
Exports both muscle nitrogen and carbon in a non-toxic form.
Alanine + alpha-ketoglutarate -> pyruvate + glutamate (liver)
Converts Alanine Alpha-ketoglutarate into Pyruvate Glutamate
› Notes
Pyruvate enters gluconeogenesis; the nitrogen passes through glutamate to the urea cycle.
Showing all 2 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real-World Patient Data.
Rajabnia M, Davoodi F, Hajisafarali M, Asadinia S, Shiri M, Shirzad F, Saeedi P, Mohammadi M. · 2026-07-09
unreviewed -
2
Open-Source Artificial Intelligence in Small-Bowel Capsule Endoscopy-Visual Assistance is Promising, But Not Yet a Standard of Care.
Toth E, Koulaouzidis A. · 2026-06-15
open access unreviewed -
3
Use of Artificial Intelligence in obtaining canine diets: nutritional inadequacy and the need for technical knowledge.
Rosa MBS, França J, Siqueira MTS, Raineri C. · 2026-07-20
unreviewed -
4
Carryover effects of dietary arginine on productive performance and blood biochemistry in Japanese quail (<i>Coturnix japonica</i>).
Gashew M, Reda GK, Knop R, Szabó C, Lendvai ÁZ, Czeglédi L. · 2026-07-19
unreviewed -
5
A novel deep learning approach for privacy-preserving encoded EEG-based brain-computer interfaces with clinical LLM applications.
Khanam T, Siuly S, Wang K, Wang H. · 2026-07-08
unreviewed -
6
Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study.
Navidifar P, Kaveh A, Hosseini SE, Keshtkar Zolghadr H, Simiyari R, Taghinasab S, Salehi MS, Kahyani A. · 2026-06-16
open access unreviewed -
7
Quantitative risk assessment of avian influenza: A scoping review.
Khoshbazm M, Spence K, Soltani M, Grant L, Yan Y, Sharif S, Dara R. · 2026-05-14
open access unreviewed -
8
Interpol review of detection of AI-generated image and video deepfakes, 2022-2025.
van Lierop S, Najdenkoska I, Worring M, Geradts Z. · 2026-06-13
open access unreviewed -
9
STARD10 promotes progression of HER2+ breast cancer and intracellular lipid metabolism via the cAMP/PKA/CREB1 signaling axis.
Liu S, Gao J, Niu Y, Dong X, Zhang Z, Teng X, Li Z, Zhang S, Meng Y, Gao MQ. · 2026-06-15
open access unreviewed -
10
Early effects of HPV vaccination on high-grade cervical intraepithelial neoplasia in Brazil: Evidence from outpatient data.
Bierrenbach AL, Pungartnik PC, Gonçalves Queijo R, Rego JG, Parellada CI. · 2026-06-15
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.