Alanine aminotransferase (ALT/GPT)
Cofactors used
What it does, reaction by reaction
Glucose-Alanine Cycle Carbohydrate Metabolism · Cytosol
Pyruvate + glutamate -> alanine + alpha-ketoglutarate (muscle)
Converts Pyruvate Glutamate into Alanine Alpha-ketoglutarate
› Notes
Exports both muscle nitrogen and carbon in a non-toxic form.
Alanine + alpha-ketoglutarate -> pyruvate + glutamate (liver)
Converts Alanine Alpha-ketoglutarate into Pyruvate Glutamate
› Notes
Pyruvate enters gluconeogenesis; the nitrogen passes through glutamate to the urea cycle.
Showing all 2 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Flushing-Assisted Saline Immersion Endoscopic Submucosal Dissection in the Rectum: A Video-Based Feasibility Series.
Matthews T, Landy J, Ban H, Toyonaga T, Suzuki N. · 2026-09-30
open access unreviewed -
2
Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real-World Patient Data.
Rajabnia M, Davoodi F, Hajisafarali M, Asadinia S, Shiri M, Shirzad F, Saeedi P, Mohammadi M. · 2026-07-09
open access unreviewed -
3
Open-Source Artificial Intelligence in Small-Bowel Capsule Endoscopy-Visual Assistance is Promising, But Not Yet a Standard of Care.
Toth E, Koulaouzidis A. · 2026-06-15
open access unreviewed -
4
Artificial intelligence catalyzes antimicrobial peptide design.
Liu Y, Hu J, Zhang N, Bai Y, Yao Y, Chen G. · 2026-07-28
open access unreviewed -
5
The perspective of artificial intelligence for NMR.
Lin Y, Zheng X, Jiang B, Chen Z, Liu M. · 2026-05-28
open access unreviewed -
6
MergeRepair: An Exploratory Study on Merging Task-Specific Adapters in Code LLMs for Automated Program Repair.
Dehghan M, Wu JJ, Fard FH, Ouni A. · 2026-09-25
open access unreviewed -
7
Vision-language models for occupational physical exposure assessment: Classification and temporal segmentation of manual material handling tasks.
Rajabi MS, Ojelade A, Kim S, Nussbaum MA. · 2026-06-05
unreviewed -
8
Media-induced indirect trauma for adolescents: a COSMIN-based systematic review of measurement instruments and their psychometric suitability.
Baek S, Lee M. · 2026-10-05
open access unreviewed -
9
Circumstances Preceding Firearm Suicide Deaths in a Large Sample of Hispanic/Latino Adults: Findings From a Content Analysis.
Abraham AM, Bailey EV, Sanger A, Naranjo DE, Wilson FA, Goldstein EV. · 2026-07-15
open access unreviewed -
10
Widespread transmission in diverse ecotypes challenges visceral leishmaniasis control in East Africa.
Iniguez E, Tuluso M, Kiplagat S, Gebresilassie A, Aklilu E, Battistoni O, Ingonga J, Makwatta JM, Alamin M, D… · 2026-09-20
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.