Mitochondrial glycerol-3-phosphate dehydrogenase (GPD2)
Cofactors used
What it does, reaction by reaction
Glycerol-3-Phosphate Shuttle Energy Metabolism & Cellular Respiration · Cytosol + inner mitochondrial membrane
Glycerol-3-phosphate + FAD -> dihydroxyacetone phosphate + FADH2
Converts Glycerol-3-phosphate FAD into Dihydroxyacetone phosphate FADH2
› Notes
Faces the intermembrane space and feeds electrons to the Q pool, so each cytosolic NADH yields only ~1.5 ATP. Dominant in skeletal muscle and brown adipose tissue.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Differential expression of mitomiRs in pancreatic islet cells associated with maternal protein restriction.
Jacovetti C, Regazzi R. · 2026-01-01
open access unreviewed -
2
Triiodothyroacetic acid exerts tissue-specific thyromimetic effects without tachycardia and hyperthermia in male mice.
Herrmann B, Adam L, Oelkrug R, Mittag J. · 2026-08-01
unreviewed -
3
Putative proteomic signatures associated with post-thaw semen quality in Peranakan Etawah and Saanen goats: an exploratory study.
Dagong MIA, Yusuf M, Diansyah AM, Matitaputty PR, Agung PP, Syarif IW, Amrullah MF. · 2026-07-27
unreviewed -
4
Lactylation landscape of mitochondrial proteins in myocardial infarction.
Kadam A, Kashyap S, Samantaray K, Jaiswal N, Goyani S, Kramer PA, Hadi P, Lee J, Furdui CM, Jadiya P, Tomar D. · 2026-05-18
open access unreviewed -
5
Ferroptosis as an approach to leverage cancer metabolism.
Jin J, Hu J, Li M, Gu W, Jiang X, Stockwell BR. · 2026-04-09
cited 1× unreviewed -
6
Biphasic Responses of Porcine Oocytes to Metformin: Concentration-Dependent AMPK Activation and Nrf2-Mediated Antioxidant Regulation
Wang J, Li M, Zhou Y, Fu F, Liu F, Tan J, Luo M, Gong S. · 2026-06-01
open access unreviewed -
7
Glycogen and Glycosylation: Friends or Foes?
Konada R, Osborn J, Mitra S. · 2026-06-01
open access unreviewed -
8
Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction.
Ikushima YM, Chen KC, Sulston RJ, Mattiucci D, Brain EJ, Fung Xin Zi SA, Suchacki KJ, Thomas BJ, Lovdel A, Be… · 2026-06-18
open access unreviewed -
9
Charge-Competition AIEgens Induce Mitochondrial Dysfunction for Selective Eradication of <i>Candida albicans</i> while Restoring Vaginal Microbiota.
Zhang R, Li X, Chen X, Shen A, Zhang X, Peng C, Qiu J. · 2026-06-12
open access unreviewed -
10
From Pathway Tracing to Actionable Targets: Integrative Mendelian Randomization and Experimental Triangulation Map Metabolic Pathways Across Ovarian Cancer Histotypes.
Wang X, Wang H, Hu S, Zhang W, Chen H, Shen Y, Xue H, Hong L. · 2026-06-02
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.