What it does, reaction by reaction
Glycogenesis (Glycogen Synthesis) Carbohydrate Metabolism · Cytosol (glycogen particle)
UDP-glucose + glycogenin–Tyr-OH → glycogenin–Tyr-O-glucose + UDP; repeated additions form a short alpha(1→4)-glucosyl primer
Converts UDP-glucose Glycogenin-Tyr-OH into Glycogenin-Tyr-O-glucose UDP Repeated additions form a short alpha(1→4)-glucosyl primer
› Notes
Glycogenin is an autoglycosylating protein that uses UDP-glucose and divalent cation (typically Mg2+). It creates the required primer, usually about 8 residues long, because glycogen synthase cannot initiate a new chain de novo.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Glycogenesis (Glycogen Synthesis)
Listed there as: Glycogenin
Availability of UDP-glucose
Lack of primer function
No major acute independent hormonal regulation
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Unmasking Compound Heterozygosity in GYG1 Myopathy: Diagnostic Insights From RNA-Seq and Long-Read Genomics.
Panwar D, Farris JD, Schmidt D, Blake EJ, Tan JW, Naddaf E, Sonnen J, Vairo FPE, Lambert LJ, Wierenga KJ, Mut… · 2026-04-23
unreviewed -
2
Phenotypic Expansion of GYG1-Related Disease Presenting as Hypertrophic Cardiomyopathy With Brugada Phenocopy.
Arat N, Cetincelik U, Gülten ZA, Sisman ST. · 2026-07-22
unreviewed -
3
ESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events.
Gherghelas AM, Toseland CP. · 2026-05-14
open access unreviewed -
4
Carbohydrate metabolism and phosphorylation cascades regulate flavor formation in chicken meat.
Yang X, Chai X, Gong J, Luo W, Xu J. · 2026-01-20
cited 1× open access unreviewed -
5
An in-depth analysis of the molecular changes induced by short-term calorie restriction before living kidney donation.
Späth MR, Arjune S, Bohl K, Rinschen MM, Falk CS, Antczak P, Grundmann F, Kubacki T, Hoyer-Allo KJR, Ignarski… · 2026-05-28
open access unreviewed -
6
Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants.
Visuttijai K, Hedberg-Oldfors C, Braun O, Englund E, Glamuzina E, Turner C, Vukusic K, Sandstedt J, Dellgren … · 2026-05-21
unreviewed -
7
Exploring biomarkers for treatment response in psoriatic arthritis: a focus on multi-omics technologies.
Khasru MR, Abdul Jalil NA, Nair N, Barton A, Martin P, Ho P, Bluett J. · 2026-05-15
open access unreviewed -
8
Discovery of molecular glues that bind FKBP12 and structurally distinct targets using DNA-encoded libraries.
Zandi TA, Romanowski MJ, Viscomi JS, Gunderson K, Tan ZY, Tong B, Bonazzi S, Zécri FJ, Schreiber SL, Michaud … · 2026-04-22
open access unreviewed -
9
Single-cell transcriptomics reveals pathogen-specific monocyte heterogeneity and potential biomarkers in gram-positive versus gram-negative bloodstream infections.
Ma J, Peng L, Yu H, Xie J, Tang Y, Su S, Ma L, Yang X. · 2026-03-01
unreviewed -
10
Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells.
Matesanz-Sánchez R, Classen S, Siniuk K, Peitzsch M, Alves T, Pospiech H, Borgmann K, Cordes N. · 2026-03-12
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.