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MS
unreviewed

Glycogenin (autoglucosylation)

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Glycogenesis (Glycogen Synthesis) Carbohydrate Metabolism · Cytosol (glycogen particle)

step 4 Irreversible/directional

UDP-glucose + glycogenin–Tyr-OH → glycogenin–Tyr-O-glucose + UDP; repeated additions form a short alpha(1→4)-glucosyl primer

Converts UDP-glucose Glycogenin-Tyr-OH into Glycogenin-Tyr-O-glucose UDP Repeated additions form a short alpha(1→4)-glucosyl primer

› Notes

Glycogenin is an autoglycosylating protein that uses UDP-glucose and divalent cation (typically Mg2+). It creates the required primer, usually about 8 residues long, because glycogen synthase cannot initiate a new chain de novo.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Glycogenesis (Glycogen Synthesis)

Listed there as: Glycogenin

Accelerated by

Availability of UDP-glucose

Inhibited by

Lack of primer function

Hormonal control

No major acute independent hormonal regulation

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
    Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis.

    Ashok D, Manjrekar PA, Shetty BC, Sailet SS. · 2026-10-01

    open access unreviewed
  2. 2
    Omics Studies in Osteoarthritis: A Review of Molecular Mechanisms and Candidate Molecules.

    Sun Y, Xiao Q, Jin M, Liu G, Zhang Q, Wei X. · 2026-09-18

    open access unreviewed
  3. 3
    TRPA1 deficiency alters brown adipose tissue proteome and thermogenic gene expression during cold exposure in mice.

    Sua-Cespedes CD, Lima OG, Vasconcelos LM, Zanetti G, Avelino da Silva M, Moraes MN, Gomes G, Festuccia WT, Ca… · 2026-08-07

    open access unreviewed
  4. 4
    Postmortem genetic testing in sudden death: clinical and medico-legal implications.

    Sabater-Molina M, Nicolas Rocamora E, Munteanu S, Fuentes Bermejo MD, Osuna E, Pérez-Cárceles MD, Pastor Quir… · 2026-05-08

    open access unreviewed
  5. 5
    Establishment and Application of a Duplex TaqMan Real-Time PCR Assay for Simultaneous Detection of Chicken Anemia Virus (CAV) and <i>Gyrovirus Galga</i> 1 (GyVg1).

    Gu KX, Ren ZH, Sun XL, Li Y, Sun T, Cui WP, Chang S, Zhao P, Gao YL, Wang YX. · 2026-08-06

    open access unreviewed
  6. 6
  7. 7
    When to think of genetic causes for rhabdomyolysis? A Brazilian single-center exploratory study.

    Martins AP, Martinez ARM, Nucci A, França Júnior MC. · 2026-08-13

    open access unreviewed
  8. 8
  9. 9
    <i>GSK3B</i> variations influence renoprotective responses to dapagliflozin in diabetic kidney disease.

    Song J, Xu Y, Zhuang Y, Yang T, Chen Y, Ying C, Lu Q, Wang T, Yin X. · 2026-07-23

    open access unreviewed
  10. 10
    UBA1 knockdown dysregulates UBA1-sensitive proteins and impairs muscle function in models of spinal muscular atrophy X-linked 2.

    Curley M, Graca FA, Stephan A, Wang W, Pagala VR, Wang YD, High AA, Demontis F. · 2026-08-26

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.