Skip to content
MS
Sign in
unreviewed

Glycogen debranching enzyme (AGL) - amylo-alpha(1,6)-glucosidase activity

1 reactions · 1 pathways

Cofactors used

H2O

Clinical / pharmacological. Cori-Forbes disease (GSD III)

What it does, reaction by reaction

1 reactions

Glycogenolysis (Glycogen Breakdown) Carbohydrate Metabolism · Cytosol + ER (liver)

step 3 Irreversible

Remaining alpha(1→6)-linked branch glucose + H2O → free glucose

Converts Remaining alpha(1→6)-linked branch glucose H2O into Free glucose

› Notes

The amylo-alpha(1,6)-glucosidase activity of the same glycogen debranching enzyme hydrolyzes the single branch-point residue using water. Approximately one glucose per branch is released free; the reaction is effectively irreversible.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Refresh

Europe PMC · from cache · sorted by publication date

  1. 1
    Presence and function of small RNAs during plant reproduction.

    Yang AS, Tang AM, Gehring M. · 2026-06-01

    open access unreviewed
  2. 2
    Cordycepin suppresses growth and virulence of <i>Magnaporthe oryzae</i> via mitochondrial function and carbonic anhydrase-associated nitrogen metabolism.

    Dang Y, Li Y, Xu G, Wang T, An Q, Gao F, Liang X, Ji X, Li Q, Wang L. · 2026-04-22

    open access unreviewed
  3. 3
    The complex subunit VdAP-2α regulates polar growth, ergosterol metabolism, and virulence in <i>Verticillium dahliae</i>.

    Wang YH, Zhu D, Wang D, Sheng RC, Wang LC, Zhang CN, Latif MF, Li H, Chen FM. · 2026-03-24

    cited 1× open access unreviewed
  4. 4
    High-Protein Diet Ameliorates Cardiomyopathy in a Cardiac-Specific AGL Knockout Mouse Model: Association With Upregulated Hepatic Gluconeogenesis.

    Du C, Fu H, Yu T, Cao S, Zhang H, Wei B, Zhang C, Ye J, Long W, Luo X, Liang Y. · 2026-09-01

    unreviewed
  5. 5
    Structures of hepatitis B virus subviral particles and identification of potential druggable pockets for the discovery of antiviral agents.

    Cuconati A, Fan KY, Tolufashe G, Zhao Q, Guo JT. · 2026-07-07

    unreviewed
  6. 6
    Typical economic activities reveal variations in microplastic pollution and ecological risks in the environment.

    Huang Y, Hu W, Zhu S, Huang Y, Cheng G, Tian P. · 2026-08-11

    unreviewed
  7. 7
    Ligase enzymes for the synthesis of peptide therapeutics.

    Gajdoš M, Xu G, Molyneux S, Micklefield J. · 2026-08-04

    unreviewed
  8. 8
    Point mutation in zinc sensor causes a threefold zinc level increase in Sorghum bicolor.

    Liao F, Blaakmeer A, Silva LS, Knudsen S, Assunção AGL. · 2026-06-16

    unreviewed
  9. 9
    Editorial: Inflammatory Bowel Disease Care Pathways-Improving Quality, but Not at Increased Cost. Authors' Reply.

    Visser EH, Voshaar MAO, van Linschoten RCA, Bodelier AGL, Fitzpatrick C, de Jonge V, Vermeulen H, Verweij KE,… · 2026-06-10

    unreviewed
  10. 10
    A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost-Effective: Results of the Multicentre IBD Value Study.

    Visser EH, Voshaar MAO, van Linschoten RCA, Bodelier AGL, Fitzpatrick C, de Jonge V, Vermeulen H, Verweij KE,… · 2026-04-23

    cited 2× unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.