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unreviewed

Glycogen debranching enzyme (AGL) - amylo-alpha(1,6)-glucosidase activity

1 reactions · 1 pathways

Cofactors used

H2O

Clinical / pharmacological. Cori-Forbes disease (GSD III)

What it does, reaction by reaction

1 reactions

Glycogenolysis (Glycogen Breakdown) Carbohydrate Metabolism · Cytosol + ER (liver)

step 3 Irreversible

Remaining alpha(1→6)-linked branch glucose + H2O → free glucose

Converts Remaining alpha(1→6)-linked branch glucose H2O into Free glucose

› Notes

The amylo-alpha(1,6)-glucosidase activity of the same glycogen debranching enzyme hydrolyzes the single branch-point residue using water. Approximately one glucose per branch is released free; the reaction is effectively irreversible.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Proteomics of heterogeneous megakaryocytes identifies JI051 as an enhancer of platelet biogenesis.

    Taga R, Kuwano N, Harada Y, Hayashi T, Sakamoto Y, Fujio K, Kakumoto Y, Nakamura E, Eto K, Hayashi H. · 2026-09-23

    open access unreviewed
  2. 2
    Low temperature modulates spike development and yield <i>via</i> ABA pathway at post-reproductive transition stage in wheat.

    Liu A, Wu S, Saeed S, Wang M, Wang X, Tu H, Yan W, He C, Wu Y. · 2026-08-25

    open access unreviewed
  3. 3
    An apoplastic effector Uv7366 contributes to <i>Ustilaginoidea virens</i> virulence and elicits plant immunity.

    Wang S, Zhang W, Zheng W, Zhang Q, Yu M, Yu J, Cao H, Pan X, Qi Z, Du Y, Zhang R, Tang B, Song T, Liu Y. · 2026-09-11

    open access unreviewed
  4. 4
    Different treatments regulate starch degradation, ethylene biosynthesis, and energy metabolism involved in the preparation and shelf life of ready-to-eat kiwifruit.

    Liu X, Tang S, Ji N, Lei J, Chen C, Zheng P, Liu B, Wang R. · 2026-06-23

    open access unreviewed
  5. 5
    Presence and function of small RNAs during plant reproduction.

    Yang AS, Tang AM, Gehring M. · 2026-06-01

    open access unreviewed
  6. 6
    Cordycepin suppresses growth and virulence of <i>Magnaporthe oryzae</i> via mitochondrial function and carbonic anhydrase-associated nitrogen metabolism.

    Dang Y, Li Y, Xu G, Wang T, An Q, Gao F, Liang X, Ji X, Li Q, Wang L. · 2026-04-22

    cited 1× open access unreviewed
  7. 7
    The complex subunit VdAP-2α regulates polar growth, ergosterol metabolism, and virulence in <i>Verticillium dahliae</i>.

    Wang YH, Zhu D, Wang D, Sheng RC, Wang LC, Zhang CN, Latif MF, Li H, Chen FM. · 2026-03-24

    cited 1× open access unreviewed
  8. 8
    Nighttime human-supervised drone-delivered automated external defibrillators: a quasi-experimental mixed-methods feasibility study.

    Chan CKJ, Ho SYJ, Yip A, Tung FLN. · 2026-09-04

    open access unreviewed
  9. 9
    Occupational exposure assessment in ROLL procedures with Tc-99m: A Monte Carlo simulation approach.

    Ferro AGL, Ferreira JRS, Souza DN, Junior ABC, Santos CJS, Neves LP, Perini AP, Belinato W, Potiens MPA, Sant… · 2026-08-14

    unreviewed
  10. 10
    <i>S</i>-Nitrosylation of glycogen phosphorylase regulates nuclear glycogenolysis and is impaired in metabolic liver disorders.

    Soria LR, D'Alessio AM, Casertano V, Polishchuk E, Pasquadibisceglie A, Boffa I, Diana A, De Cegli R, De Stef… · 2026-10-02

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.