What it does, reaction by reaction
Purine De Novo Synthesis (IMP synthesis through to AMP/GMP) Nucleotide Metabolism · Cytosol
FGAR → formylglycinamidine ribonucleotide (FGAM)
Converts Formylglycinamide ribonucleotide (FGAR) into Formylglycinamidine ribonucleotide (FGAM)
› Notes
FGAM synthetase catalyzes FGAR + glutamine + ATP + H2O → FGAM + glutamate + ADP + Pi. The glutamine-derived nitrogen becomes N3 of the purine ring; ATP activates the formyl group before amidination.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
An integrated workflow for combined organic and inorganic chemical exposome analysis.
Braeuer S, Feuerstein ML, Buerki-Thurnherr T, Warth B, Koellensperger G. · 2026-08-22
unreviewed -
2
Semiquantification of PFAS in nontarget analysis via ionization efficiency: A critical review of evidence and validation frameworks.
Xin X, Wang H, Wang Z, Wang Y, Zhang C, Yu K, Hou P, Dong H. · 2026-08-06
unreviewed -
3
A simple and sensitive QuEChERS-based LC-MS/MS method for quantifying 30 per- and polyfluoroalkyl substances (PFAS) in human serum: application to firefighter biomonitoring.
Sweeney CL, Suwanratanabus R, Seyedsadjadi N, Nguyen D, Rennert J, Masoud F. · 2026-08-05
unreviewed -
4
Environmental and Occupational Risk Factors for Retinoblastoma.
Bowen RA, Woodring TS, Monroe EJ, Bedno SA. · 2026-07-21
open access unreviewed -
5
Embryonic exposure to ambient concentrations of PFAS impairs the innate immune response in zebrafish and fathead minnow.
Lyons S, Yu AM, Dehnert GK, King Heiden TC. · 2026-09-10
unreviewed -
6
Interpol review of forensic drug chemistry, 2022-2025.
Love D, Page E. · 2026-08-16
open access unreviewed -
7
Awareness, cultural importance, risk perception and consumption behavior - the issue of contaminants in pilot whales in the Faroe Islands.
Helmsdal EF, Á Fríðriksmørk Borðoy R, Nielsen JB, Skaalum Petersen M. · 2026-08-21
open access unreviewed -
8
Adaptive strategies of emergent plants to per- and polyfluoroalkyl substances.
Gao C, Hua ZL, Gu L. · 2026-08-18
unreviewed -
9
Behavioral effects of chronic PFHxA exposure on spatial memory function.
Lee DH, Cho B, Seo J, So YH, Shin HS, Lim D, Hwang I, Lee EH, An BS, Jung EM. · 2026-08-10
unreviewed -
10
Thermally controlled microdroplet formation generated by fatty acid oil.
Shojania Feizabadi M, Paisnel JW, Stanisic J. · 2026-07-22
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.