Enoyl-ACP reductase (ER) domain of FAS
Cofactors used
What it does, reaction by reaction
Fatty Acid Synthesis (De Novo Lipogenesis) Lipid Metabolism · Cytosol
trans-Δ2-Enoyl-ACP + NADPH + H+ → saturated acyl-ACP + NADP+
Converts trans-Delta-2-Enoyl-ACP NADPH H+ into Saturated acyl-ACP NADP+
› Notes
Enoyl-ACP reductase (ER) completes the second reduction of the cycle using NADPH. Steps 8–11 repeat seven times, adding two carbons per cycle and converting the primer ultimately to palmitoyl-ACP.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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