What it does, reaction by reaction
1 reactions
Vitamin D Activation Cofactor & Vitamin Metabolism · Skin, liver ER, renal proximal tubule mitochondria
step 4
Irreversible/directional
25-OH-D or calcitriol -> 24,25-(OH)2-D / calcitroic acid
Converts 25-OH-D or calcitriol into 24,25-(OH)2-D / calcitroic acid
› Notes
Inactivation arm; induced by calcitriol. Loss-of-function causes idiopathic infantile hypercalcaemia.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
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