Cholesterol
Reactions involving Cholesterol
Every recorded step where this molecule takes part
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Cholesterol + O2 + NADPH -> 7-alpha-hydroxycholesterol
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consumed Cholesterol 7-alpha-hydroxylase (CYP7A1) Lipoprotein Metabolism (Exogenous and End… ST-0132
Hepatic cholesterol → bile acids/free cholesterol → biliary secretion or enterohepatic recycling
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produced Monoacylglycerol acyltransferase + DGAT + ACAT2 (enterocyte) Lipoprotein Metabolism (Exogenous and End… ST-0117
Fatty acids/monoacylglycerol + enterocyte re-esterification → TAG; cholesterol → cholesteryl ester
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produced SR-BI (selective uptake) / CETP (cholesteryl ester transfer protein) Lipoprotein Metabolism (Exogenous and End… ST-0131
HDL cholesteryl ester → liver directly or to apoB particles indirectly
Showing all 4 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Lipoprotein Metabolism (Exogenous and Endog… | → | Bile Acid Synthesis | within category |
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Advances and perspectives in genetically encoded biosensors for biomarker detection and theranostic circuits.
Xu J, Qi Q, Wang Q. · 2026-09-23
open access unreviewed -
2
Combinatorial metabolic engineering of <i>Mycobacterium neoaurum</i> LY-2 for efficient androstenedione production from phytosterols.
Xu L, Peng C, Pan W, Tong Y, Shi J, Xu Z, Li H. · 2026-08-19
open access unreviewed -
3
In situ bioactive nanocoating enables transocular delivery of permeable drug for dual-location intervention of ocular surface and fundus disorders.
Wang Z, Lv W, Su Y, Yao T, Lu Y, Wang C, Wang C, Yu Y, Chen J, Qi Q, Pang Y, Wang Z, Wu F. · 2026-09-22
open access unreviewed -
4
A programmable spatiotemporal bioelectrical conduit promotes peripheral nerve regeneration by suppressing ferroptosis through modulation of ER-mitochondria coupling in Schwann cells.
Wang Z, Jiang A, Wang F, Yang Z, Zhong Y, Yang Y, Tan J, Han W, Li X, He X, Zhang X, Wang J, Han X, Bai D. · 2026-09-16
open access unreviewed -
5
A transferrin receptor-targeted liposome for iron metabolism regulation-augmented photodynamic therapy in glioblastoma.
Wen R, He G, Wan Y, Guo X, Xiong S, Wu Y, Wei Y, Li D, Lin J, Huang P. · 2026-09-16
open access unreviewed -
6
An oral coral-like resveratrol nanocomplex protects against dry eye disease through ocular and systemic redox homeostasis.
Cui Q, Li Y, Xie M, Liu Z, Guo Y, Zang Y, Bao J, Wu Q, Tian L, Jie Y. · 2026-09-04
open access unreviewed -
7
From RNA design to delivery: Computational strategies for functional RNA therapeutics.
Wang Y, Tong S, Wang X, Jin X, Tan D, Lu Y. · 2026-08-31
open access unreviewed -
8
Bioactive glasses-mediated ion therapy ameliorates hepatic osteodystrophy by reprogramming the liver-bone axis.
Liu SC, Xie E, Zhao P, Liu YS, Xie ZY, Chang HD, Zhao WD, Huang PY, Zhu YX, Rehman MAU, Gao Y, Urbani L, Gou … · 2026-08-31
open access unreviewed -
9
3D-printed niche-matched GelMA-dECM bioinks rewire lipid metabolic reprogramming and chemosensitization in pancreatic ductal adenocarcinoma.
Zhu B, Yang T, Chang M, Li Y, Wu D, Yan J, Guo Q, Wan J, Guo Y, Lu Y. · 2026-08-20
unreviewed -
10
Transient culture of adult human hepatocytes as organoids improves engineered liver engraftment.
Saxton SH, Kang I, Mitchell S, Lotto J, Upadhyay A, Zou C, Quirk C, McCray TN, Prado O, Johansson F, Fortin C… · 2026-07-23
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.