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MS
unreviewed

Monoacylglycerol acyltransferase + DGAT + ACAT2 (enterocyte)

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Lipoprotein Metabolism (Exogenous and Endogenous Pathways: chylomicrons, VLDL, LDL, HDL) Lipid Metabolism · Intestine, liver, plasma, capillary endothelium

step 2 Irreversible/directional

Fatty acids/monoacylglycerol + enterocyte re-esterification → TAG; cholesterol → cholesteryl ester

into Triacylglycerol (TAG) Cholesterol

Notes

Enterocytes re-form TAG mainly through the monoacylglycerol pathway (monoacylglycerol acyltransferase and DGAT) and esterify cholesterol through acyl-CoA:cholesterol acyltransferase 2 (ACAT2). These reactions use activated fatty acyl-CoA; long-chain lipids are assembled for export.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

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