5-Methyl-THF
Reactions involving 5-Methyl-THF
Every recorded step where this molecule takes part
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Homocysteine + 5-methyl-THF → methionine + THF
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5-Methyl-THF + homocysteine → THF + methionine
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5,10-Methylene-THF + NADPH + H⁺ → 5-methyl-THF + NADP⁺
Showing all 3 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| One-Carbon Metabolism (Folate Cycle) | → | Methionine Cycle / Transmethylation (SAM Cy… | within category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Methionine Synthase Interacts With the Methionine Adenosyl-Transferase MATα2 and the DNA Methyltransferase DNMT3b in the Nucleus.
Jeandel M, Alberto JM, Baspinar O, Robert A, Dreumont N, Alsahly Z, Meyre D, Guéant JL, Coelho D. · 2026-07-01
open access unreviewed -
2
A Systematic Review of Folate and the Human Enteric Microbiome: Biological Mechanisms and Clinical Implications.
Khanduja R, Frye RE. · 2026-06-03
open access unreviewed -
3
SIN-3 coregulator maintains adaptive capacity to different diets in Caenorhabditis elegans through vitamin B12.
Palladino F, Bedet C. · 2026-06-01
open access unreviewed -
4
One-carbon metabolism and cardiovascular disease: Molecular mechanisms, genetic influences, and epigenetic regulation.
Al Qassab M, Bou Ghanem A, Hussayni Y, Kadbey R, Ratel Y, Yehya S, Zahr M, Ghadieh HE, Abi Khattar Z, Azar S,… · 2026-03-17
open access unreviewed -
5
The complex link of the folate-homocysteine axis to myocardial hypertrophy and heart failure: from mechanistic exploration to clinical vision.
Wang Y, LaBapuchi, Liu M, Chen L. · 2025-09-19
cited 1× open access unreviewed -
6
Nutrient-Sensitive Epigenetic Modifiers as Candidate Biomarkers of Metabolic Dysfunction in Obesity: A Nutrigenomic Review.
Rodríguez-Vera D, Gómez-Martínez MA, Herrera-Picazo MV, Robledo LA, Tufiño C, Bustamante-Tenorio CC, Soriano-… · 2026-05-14
open access unreviewed -
7
Glucarpidase efficacy in mitigating methotrexate toxicity is unaffected by concurrent administration of folinic acid.
Wahlestedt M, Hansson K, Bill A, Isaksson A, Heldrup J, Pronk CJ. · 2026-05-08
open access unreviewed -
8
Emerging mechanistic trends and clinical efficacy for methotrexate: Applications to inflammatory bowel disease.
You JK, Pizarro TT, Parigi TL. · 2026-03-19
open access unreviewed -
9
Mutation of active site glutamate in serine hydroxymethyltransferase allows trapping a reactive intermediate: a combined neutron and X-ray crystallography study.
Drago VN, Phillips RS, Kovalevsky A. · 2026-04-01
open access unreviewed -
10
Optimisation of Micronutrient Supplementation During Pregnancy: Interactions Between Bioactive Compounds, Their Impact on Health, and Regulatory Considerations.
Makó RA, Sipos P. · 2026-04-05
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.