Thiamine pyrophosphate (TPP)
Reactions involving Thiamine pyrophosphate (TPP)
Every recorded step where this molecule takes part
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Pyruvate + thiamine pyrophosphate (TPP) → hydroxyethyl-TPP + CO2
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Pyruvate + TPP → hydroxyethyl-TPP + CO2
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Hydroxyethyl-TPP + oxidized lipoamide (E2) → acetyl-lipoamide + TPP
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Hydroxyethyl-TPP + oxidized lipoamide-E2 → acetyl-dihydrolipoamide-E2 + TPP
Showing all 4 reactions.
Pathway junctions through this molecule
Produced in one pathway, consumed in another
| Produced in | Consumed in | Link | |
|---|---|---|---|
| Pyruvate Dehydrogenase Complex (Link Reacti… | → | Pyruvate Oxidation / Link Reaction (Pyruvat… | cross-category |
| Pyruvate Oxidation / Link Reaction (Pyruvat… | → | Pyruvate Dehydrogenase Complex (Link Reacti… | cross-category |
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Metabolic pathway analysis reveals hierarchical pentose sugar utilization and metabolic flexibility of <i>Bifidobacterium longum</i>.
Friess L, McAuliffe FM, Cotter PD, Shiver AL, Huang KC, de Jong A, van Sinderen D. · 2026-03-23
open access unreviewed -
2
Formate as electron carrier in the gut acetogen <i>Blautia luti</i>: a model for electron transfer in the gut microbiome.
Trischler R, Müller V. · 2026-01-02
cited 2× open access unreviewed -
3
Evaluation of Ogataea polymorpha DUR31 TPP riboswitch as a tool to downregulate gene expression in the yeast Komagataella phaffii.
Małecki P, Gasser B. · 2026-06-29
unreviewed -
4
Engineering thiamine pyrophosphate metabolism improves consolidated bioprocessing for cellulosic ethanol with inorganic nitrogen in Myceliophthora thermophila.
Chen J, Liu J, Sun T, Pang R, Yu J, Liu D, Li J, Tian C. · 2026-06-30
unreviewed -
5
Effects of Different Rearing Systems (Cage vs. Free-Range) on Growth Performance, Serum Biochemical Parameters, Slaughter Performance, Cecal Microbiota, and Hepatic Metabolism of Yellow-Feathered Broilers
Nie X, Li J, Cui Y, Yuan J, Li F, Chen Y, Liu J. · 2026-06-01
open access unreviewed -
6
Upcycling Discarded Apples into Cider: Yeast and Nutrient Strategies Shaping Fermentation and Sensory Quality
Marques-Gomes C, Cardeal B, Inês A, Cosme F, Falco V, Vilela A. · 2026-06-01
open access unreviewed -
7
Engineering of Corynebacterium glutamicum for biosynthesis of the pharmaceutically active N-acetyltyramine: establishing and optimizing de novo production.
Poethe SS, Kaimann LS, Schülke KH, Hammer SC, Wendisch VF. · 2026-06-18
open access unreviewed -
8
Hippocampal, Microglial, Morphological, and Amyloid Profiles Following Thiamine Pyrophosphate Treatment in 3xTg-AD Mice.
Pastén-Castrejón NJ, Martínez-Orozco H, Gutiérrez-Silerio GY, Hernández-Montiel HL, Maya-Arteaga JP, Poblano-… · 2026-06-02
open access unreviewed -
9
A thiadiazolylidene-morpholine compound inhibits Pseudomonas aeruginosa by destabilizing the thiamine monophosphate kinase thiL.
Li Y, Lin J, Chung Z, Yee Yeo BK, Lescar J, Pethe K. · 2026-05-06
open access unreviewed -
10
Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p-cresol Formation.
Jiang L, Wei Y, Liu X, Liu D, Liu Z, Tong Y, Yin J, Urs ANN, Xing M, Harrison MA, Zhang C, Yang S, Luo Y, Ang… · 2026-03-31
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.