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MS
unreviewed

Cytidine deaminase

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Pyrimidine Degradation Nucleotide Metabolism · Cytosol

step 2 Irreversible/directional

CMP (or cytidine) → uridine

Converts CMP into Uridine

Notes

Cytidine deaminase catalyzes cytidine + H2O → uridine + NH3; after CMP is dephosphorylated, this reaction funnels cytosine nucleosides into uracil catabolism. Cytidine deaminase also acts on deoxycytidine to form deoxyuridine and is clinically important in nucleoside drug metabolism.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
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    <i>Streptomyces</i>: boost chassis strains for production of invaluable natural products.

    Chen S, Ling S, Li J, Liu Z, Zhang L, Zhang J. · 2026-06-12

    open access unreviewed
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    Antibiotic-drug conjugates: Enhancing chemo-immunotherapy of gemcitabine for pancreatic cancer by eliminating intratumoral bacteria.

    Zhang Z, Zhang F, Yang W, Xu J, Peng Z, Zhao X, Wei Y, Li G, Xie W, Wang X. · 2026-06-12

    unreviewed
  5. 5
    Mitophagy in cisplatin-induced kidney injury: regulatory mechanisms and therapeutic targets.

    Yuan C, Jiang J, Ji J, Ni L. · 2026-05-27

    open access unreviewed
  6. 6
    NVX-CoV2372, monovalent mRNA and bivalent mRNA vaccines elicit broadly cross-reactive antibodies against emerging SARS-CoV-2 variants.

    Poh XY, Mah SYY, Yeoh AYY, Chavatte JM, Lim DRX, Tan CCY, Tang HL, Gandhi M, Rahman N, Rao S, Chia PY, Sadara… · 2026-05-05

    open access unreviewed
  7. 7
  8. 8
    Microbiota as a modulator of drug response: targeting microbial-drug crosstalk in cancer therapy.

    Zhao T, Liu M, Qiu L, Zhang H, Zhang N, Liu Z, Xia Z, Luo P, Huang J, Cheng Q. · 2026-04-10

    open access unreviewed
  9. 9
    Glycan pairing in therapeutic IgG orchestrates Fcγ receptor engagement and ADCC: an integrated structure-function approach for thorough evaluation of Fc N-glycans as critical quality attributes.

    Meudt M, Baumeister J, Russell AC, Dzielak L, Hansen G, Mizaikoff B, Ebert S, Rosenau F, Blech M, Higel F. · 2026-04-02

    open access unreviewed
  10. 10
    PD-1 blockade promotes mucosal CD4+ T cell IL-10 production through altering microbiota to reduce intestinal ischemia reperfusion injury.

    Wen SH, Zhang YN, Shen JT, Guo Y, Chang ZN, Zhang HF, Liu ZM, Zhang XY. · 2026-03-06

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.