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MS
unreviewed

Choline kinase

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Phospholipid Synthesis (Kennedy / CDP pathways) Lipid Metabolism · ER / Golgi

step 1 Irreversible/directional

Choline + ATP -> phosphocholine + ADP

Converts Choline ATP into Phosphocholine ADP

Notes

Dietary/salvaged choline is trapped by phosphorylation.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
  2. 2
    Preclinical efficacy of a gene therapy for <i>CHKB</i>-mediated muscular dystrophy.

    Tavasoli M, Alkandari M, Dorighello G, Devitt J, Hagerty L, Damsker J, Hoffman EP, McMaster CR. · 2026-05-25

    open access unreviewed
  3. 3
  4. 4
  5. 5
    Choline kinase beta promotes psoriasis pathogenesis by regulating sphingolipid metabolism and activating the PI3K/Akt/GSK3β signaling pathway.

    Luo M, Gao J, Jiang M, Zhang Y, Long D, Yan Y, Pan Y, Zhou R, Fang H, Wang H. · 2026-04-23

    unreviewed
  6. 6
  7. 7
  8. 8
    Oncogenic snoRNA <i>SNORD78</i> fuels colorectal cancer by protecting the m<sup>6</sup>A reader IMP2 to enhance phospholipid metabolism.

    Zhao Y, Hu X, Li Y, Zhang J, Guo H, Zhang Y, Wu T, Guo J, Peng Y, Che Y, Zhu X, Chen Q, Grieve D, Wei M, Wu H. · 2026-07-14

    unreviewed
  9. 9
  10. 10
    Structural and biochemical comparison of the FLVCR and CTL membrane protein families in eukaryotes.

    Nel L, Driller JH, Driller R, Frain KM, Pedersen BP. · 2026-05-11

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.