What it does, reaction by reaction
Phospholipid Synthesis (Kennedy / CDP pathways) Lipid Metabolism · ER / Golgi
Choline + ATP -> phosphocholine + ADP
Converts Choline ATP into Phosphocholine ADP
› Notes
Dietary/salvaged choline is trapped by phosphorylation.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Corrigendum to "Choline kinase beta promotes psoriasis pathogenesis by regulating sphingolipid metabolism and activating the PI3K/Akt/GSK3β signaling pathway" [Biochim. Biophys Acta (BBA) - Mol. Basis Dis. Volume 1872, Issue 6 (2026) 168275].
Luo M, Gao J, Jiang M, Zhang Y, Long D, Yan Y, Pan Y, Zhou R, Fang H, Wang H. · 2026-08-29
unreviewed -
2
HSV-1 metabolic hijacking: Mechanisms to precision therapeutics.
Kuang S, Zhang J, Chen J, He Z, Yang J, Li S, Ding J, Ma Z, Zhang B. · 2026-08-11
open access unreviewed -
3
Kaempferol activity on <i>Cryptosporidium parvum</i> infection in an experimentally infected immunocompromised mouse model: <i>In silico</i> and <i>in vivo</i> investigations.
Wakid MH, El-Wakil ES, Alsulami MN, Azab H. · 2025-12-19
open access unreviewed -
4
Chemoenzymatic Synthesis of (4R,7R)‐Zingiberene Enables Construction of nor‐Sesquiterpene Semiochemical Analogs
Johnson L, Benton J, Jones C, Kuzba O, Miller D, Pickett J, Allemann R. · 2026-10-06
open access unreviewed -
5
Tumor-derived acetylcholine promotes immune evasion in hepatocellular carcinoma by protecting regulatory T cells from ferroptosis.
Liu F, Liu Z, Wang J, Wu J, Xu Y, Zeng Q, Yuan J, Tang L, Yang J, Han J. · 2026-10-01
unreviewed -
6
<sup>1</sup>H HR-MAS NMR Metabolomics in Combination With Transcriptomic Correlation Provides New Insights Into Metabolic Heterogeneity Across Breast Cancer Immunohistochemical Subtypes.
Garcia-Bocanegra I, Urbano-Gamez JD, Perez-Cardona A, Barrios L, Somoza-Ramírez MI, Vicioso L, Pardo-Susacasa… · 2026-10-01
open access unreviewed -
7
Comparison of coronal and sagittal pelvic-lower limb alignment after open wedge distal tibial tuberosity osteotomy and total knee arthroplasty using the EOS imaging system.
Kim Y, Tomura J, Nakamura K, Yoshida K, Hada S, Shiozawa J, Kaneko H, Saita Y, Kubota M, Ishijima M. · 2026-08-19
open access unreviewed -
8
Subtype-specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review).
Ran Y. · 2026-08-04
open access unreviewed -
9
LC-MS/MS and high-spatial single-cell MSI reveal selective downregulation of PC(16:0_16:0) and PC(18:0_18:1) due to mPGES-1 knockdown in hormone-resistant prostate cancer cell line.
Afroz MS, Aramaki S, Rahman MM, Dubail M, Chi Z, Fujii K, Kurosawa M, Tamura K, Kahyo T, Nakamura K, Inamoto … · 2025-12-23
cited 1× open access unreviewed -
10
Multiomic Profiling Links RDH12-Dependent Retinaldehyde Detoxification to Membrane Remodeling and Ferroptosis
· 2026-09-28
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.