Skip to content
MS
Sign in
unreviewed

Alanine aminotransferase (ALT / GPT)

1 reactions · 1 pathways

Cofactors used

PLP (B6) · B6 (Pyridoxine)

What it does, reaction by reaction

1 reactions

Transamination Amino Acid & Nitrogen Metabolism · Cytosol + mitochondrion

step 3 Reversible

L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate

Converts Alanine Alpha-ketoglutarate into Pyruvate Glutamate

› Notes

Alanine aminotransferase (ALT/GPT) catalyzes this PLP-dependent, reversible reaction. In the glucose–alanine cycle, muscle exports alanine and liver converts it to pyruvate for gluconeogenesis while retaining the nitrogen as glutamate.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Refresh

Europe PMC · from cache · sorted by publication date

  1. 1
    Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real-World Patient Data.

    Rajabnia M, Davoodi F, Hajisafarali M, Asadinia S, Shiri M, Shirzad F, Saeedi P, Mohammadi M. · 2026-07-09

    unreviewed
  2. 2
    Open-Source Artificial Intelligence in Small-Bowel Capsule Endoscopy-Visual Assistance is Promising, But Not Yet a Standard of Care.

    Toth E, Koulaouzidis A. · 2026-06-15

    open access unreviewed
  3. 3
    Use of Artificial Intelligence in obtaining canine diets: nutritional inadequacy and the need for technical knowledge.

    Rosa MBS, França J, Siqueira MTS, Raineri C. · 2026-07-20

    unreviewed
  4. 4
    Carryover effects of dietary arginine on productive performance and blood biochemistry in Japanese quail (<i>Coturnix japonica</i>).

    Gashew M, Reda GK, Knop R, Szabó C, Lendvai ÁZ, Czeglédi L. · 2026-07-19

    unreviewed
  5. 5
    A novel deep learning approach for privacy-preserving encoded EEG-based brain-computer interfaces with clinical LLM applications.

    Khanam T, Siuly S, Wang K, Wang H. · 2026-07-08

    unreviewed
  6. 6
    Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study.

    Navidifar P, Kaveh A, Hosseini SE, Keshtkar Zolghadr H, Simiyari R, Taghinasab S, Salehi MS, Kahyani A. · 2026-06-16

    open access unreviewed
  7. 7
    Quantitative risk assessment of avian influenza: A scoping review.

    Khoshbazm M, Spence K, Soltani M, Grant L, Yan Y, Sharif S, Dara R. · 2026-05-14

    open access unreviewed
  8. 8
    Interpol review of detection of AI-generated image and video deepfakes, 2022-2025.

    van Lierop S, Najdenkoska I, Worring M, Geradts Z. · 2026-06-13

    open access unreviewed
  9. 9
    STARD10 promotes progression of HER2+ breast cancer and intracellular lipid metabolism via the cAMP/PKA/CREB1 signaling axis.

    Liu S, Gao J, Niu Y, Dong X, Zhang Z, Teng X, Li Z, Zhang S, Meng Y, Gao MQ. · 2026-06-15

    open access unreviewed
  10. 10
    Early effects of HPV vaccination on high-grade cervical intraepithelial neoplasia in Brazil: Evidence from outpatient data.

    Bierrenbach AL, Pungartnik PC, Gonçalves Queijo R, Rego JG, Parellada CI. · 2026-06-15

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.