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MS
unreviewed

Adenine phosphoribosyltransferase (APRT)

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Purine Salvage Pathway Nucleotide Metabolism · Cytosol

step 3 Irreversible

Adenine → AMP

Converts Adenine into AMP

Notes

Adenine phosphoribosyltransferase (APRT) catalyzes adenine + PRPP → AMP + PPi. The reaction uses PRPP and Mg2+ and is effectively irreversible because cellular pyrophosphatases hydrolyze PPi.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · from cache · sorted by publication date

  1. 1
    Development of a qualitative detection method for the pSIM1278 construct in genetically modified potato using real-time PCR.

    Sugino M, Soga K, Narushima J, Matsumoto M, Takabatake R, Yoshiba S, Shibata N. · 2026-04-24

    open access unreviewed
  2. 2
    Nutritional supplements to improve esports player performance: a systematic review of randomized controlled trials.

    Huang D, Zheng Y, Xu M, Huang W. · 2025-12-22

    cited 1× open access unreviewed
  3. 3
  4. 4
  5. 5
    2,8-Dihydroxyadenine Crystal Nephropathy and Mediators of Kidney Injury in Adenine Phosphoribosyltransferase Deficiency.

    Helgudottir HR, Runolfsdottir HL, Hardarson S, Palsson R, Edvardsson VO, Gudjonsson T. · 2026-07-28

    unreviewed
  6. 6
  7. 7
    Survey of Canadian specialised palliative radiotherapy programs.

    Rau A, Bayley C, Dennis K, Hoegler D, Kerba M, Fairchild A. · 2026-03-26

    open access unreviewed
  8. 8
    Family-Based Study Reveals PDE11A/PDE11A-AS1 Variants in Testicular Germ Cell Tumor Predisposition

    Côrtes L, Rodrigues A, Silveira S, Ramírez-Mejía J, Dreyer C, Aagaard M, Fernandez G, Lopes A, Filho J, Rogat… · 2026-06-01

    open access unreviewed
  9. 9
  10. 10
    Analysis of the Subculture Effect on the <i>Auricularia heimuer</i> Strain 'HWS1908' Based on Transcriptome.

    Han C, Zhang X, Guo Y, Ma Y, Tian S, Dai X, Zhang P. · 2026-06-15

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.