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MS
unreviewed

Uridine phosphorylase

1 reactions · 1 pathways

Cofactors used

What it does, reaction by reaction

1 reactions

Pyrimidine Degradation Nucleotide Metabolism · Cytosol

step 3 Irreversible/directional

Uridine → uracil

Converts Uridine into Uracil

› Notes

Uridine phosphorylase catalyzes uridine + Pi ⇌ uracil + ribose 1-phosphate. Deoxyuridine can similarly be phosphorolyzed to uracil plus deoxyribose 1-phosphate.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

Europe PMC · fetched just now · sorted by publication date

  1. 1
  2. 2
    Gene variants associated with pediatric-onset erythromelalgia: Mendelian and rare-variant association analyses.

    Yonas MC, Ocay DD, Genetti CA, Lobo K, Fernandes M, Groussis N, Halpin M, Wilder RT, Yu TW, Berde CB, Brownst… · 2026-08-03

    open access unreviewed
  3. 3
    1,2,4-Triazolium compounds as anti-oomycete leads against Phytophthora capsici.

    Song J, Zhang X, Zhang A, Li T, Chi YR. · 2026-06-09

    unreviewed
  4. 4
  5. 5
    Omics Studies in Osteoarthritis: A Review of Molecular Mechanisms and Candidate Molecules.

    Sun Y, Xiao Q, Jin M, Liu G, Zhang Q, Wei X. · 2026-09-18

    open access unreviewed
  6. 6
  7. 7
    Ribonucleotides Amplify Mitochondrial DNA-Driven cGAS-STING Activation via FdUMP-ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy.

    Wang C, Zhao C, Yao Y, Zou Z, Shi A, Feng Z, Yang M, Yu Y, Liu Y, Rui X, Wu J. · 2026-09-21

    open access unreviewed
  8. 8
    Siglec-15 promotes a feed-forward loop between TNBC cells and macrophages via the NF-κB/DcR3/CCL18/STAT3 axis.

    Wang S, Wang HQ, Zhao H, Zhao R, Zhao P, Mu Q. · 2026-09-18

    open access unreviewed
  9. 9
    Japanese encephalitis virus reprograms host pyrimidine metabolism to facilitate viral replication.

    Gu J, Fan C, Xiang S, Si Y, Zhu B, Cao S, Ye J. · 2026-07-31

    open access unreviewed
  10. 10
    Machine Learning-Derived Immune Gene Signature Predicts Prognosis and Therapeutic Vulnerabilities in Multiple Myeloma.

    Wang K, Zhao C, Shi J, Liu S, Chen Y, Wang J, Sun Z, Wang S, Fan L, Fan J, Qu X. · 2026-09-06

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.