What it does, reaction by reaction
Pyrimidine De Novo Synthesis (through to UMP, then CTP/dTMP) Nucleotide Metabolism · Cytosol (one mitochondrial step)
UMP → UDP
› Notes
UMP/CMP kinase catalyzes UMP + ATP → UDP + ADP. Mg2+ is required; this is the first phosphorylation needed to build the UTP pool.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20-Mediated CMPK2 Palmitoylation.
Wang Y, Cui Z, Zhang Y, Li Z, Cao X. · 2026-04-21
unreviewed -
2
Host metabolic responses to SARS-CoV-2 and influenza viruses: parallels and contrasts.
Terra C, Terrier O, Le Gouellec A. · 2026-06-02
open access unreviewed -
3
Integrated Analysis of Transcriptome and Metabolome Reveals Molecular Responses to Ammonia Stress in the Gills of <i>Litopenaeus vannamei</i> Under Low-Salinity Conditions.
Zhao Y, Ding Y, Zhou F, Hu X, Yang Q, Cao Y. · 2026-04-13
open access unreviewed -
4
Multienzyme Platform for the Synthesis of UDP Sugars and Human Milk Oligosaccharides.
Hoang TS, Lange F, Kleeberg SB, Thomas L, Hoang NH, Reichl U, Rexer TFT. · 2026-04-01
open access unreviewed -
5
Comprehensive Human Red Blood Cell Membrane and Cytoplasmic Proteome Analyses.
Zhang X, Liu H, Zhang Q, Liu T, Qi S, Wang L, Yang W, Sha J, Geng Z, Du L, Hu Q, Cai M, Chen D, Chen Y, Liu S… · 2026-02-07
cited 1× open access unreviewed -
6
Cellular pharmacology of fludarabine: molecular determinants of transport and metabolism.
Mseddi M, Mlakar V, Gloor Y, Gonzales F, Baleydier F, Daali Y, Ansari M. · 2026-05-19
cited 1× open access unreviewed -
7
Shoot transcriptome and co-expression network analysis of African rice cultivars identify drought-tolerance hub genes and growth stage-dependent trade-offs.
Adjah KL, Aziadekey M, Toure A, Asante MD, Tawiah I, Yadav S, Onaga G, Amoah NKA, El-Namaky R, Agboka K, Henr… · 2026-04-15
open access unreviewed -
8
Omics Reveals the Antibacterial Mechanism of Dihydromyricetin and Vine Tea Extract Against <i>Staphylococcus aureus</i> via Cell Wall and Membrane Disruption.
Hui Q, Li T, He K, Ma W, Guo Y, Zhang Y, Song L. · 2026-01-16
open access unreviewed -
9
Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism.
Nishiwaki A, Okanishi H, Kanai Y, Masui R. · 2025-09-15
open access unreviewed -
10
Validated antimalarial drug target discovery using genome-scale metabolic modeling.
Taweechai S, Totañes FIG, Westhead D, Herrera-Arozamena C, Foster R, McConkey GA. · 2025-09-26
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.