What it does, reaction by reaction
Pyrimidine De Novo Synthesis (through to UMP, then CTP/dTMP) Nucleotide Metabolism · Cytosol (one mitochondrial step)
UMP → UDP
› Notes
UMP/CMP kinase catalyzes UMP + ATP → UDP + ADP. Mg2+ is required; this is the first phosphorylation needed to build the UTP pool.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Combining automated kinetic model selection with robust optimization and application to maximize cell-free production of UDP-GalNAc.
Huber N, Hoang TS, Espinel Ríos S, Rexer TFT, Reichl U, Klamt S. · 2026-09-08
open access unreviewed -
2
MIND diet–related plasma proteins are associated with Alzheimer's disease risk
Fernandez S, Dempsey D, Chaudhuri S, Huang Y, Park T, Liu S, Unverzagt F, Gao S, Wilcock D, Yang J, Rebholz C… · 2026-10-01
open access unreviewed -
3
Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis.
da Silva Bonjour M, Rinaldi AJ, Dos Santos EGD, Faria GTB, de Azevedo Manhães AME, Pereira JF, Auad AM, de Al… · 2026-06-12
cited 1× open access unreviewed -
4
Mechanisms of chemoresistance in gastric cancer: interplay between microRNAs and the tumor microenvironment.
Ilie VC, Minciuna CE, Andras C, Turcu SN, Herlea V, Dima SO, Droc G, Lacatus M, Tudor S, Vasilescu C. · 2026-05-06
cited 1× open access unreviewed -
5
Nuclear proteome analysis suggests spatial and temporal compartmentalization of metabolic enzymes during Trypanosoma cruzi cell cycle.
Menezes AP, Gachet-Castro C, McGill S, Burchmore R, Silber A, Elias MC, da Cunha JPC. · 2026-09-28
open access unreviewed -
6
Ribonucleotides Amplify Mitochondrial DNA-Driven cGAS-STING Activation via FdUMP-ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy.
Wang C, Zhao C, Yao Y, Zou Z, Shi A, Feng Z, Yang M, Yu Y, Liu Y, Rui X, Wu J. · 2026-09-21
open access unreviewed -
7
Japanese encephalitis virus reprograms host pyrimidine metabolism to facilitate viral replication.
Gu J, Fan C, Xiang S, Si Y, Zhu B, Cao S, Ye J. · 2026-07-31
open access unreviewed -
8
Proteome of Human Scalp Hair Follicles.
Hegde A, Srinivasan Y, Chavan MA, Kalsi G. · 2026-08-24
open access unreviewed -
9
Gemcitabine-based chemotherapy for advanced biliary tract carcinomas.
Awedew AF, Fentahun Emrie A, Jegnie M, Morales L, supported by the Cochrane Hepato-Biliary Group. · 2026-08-17
open access unreviewed -
10
Nucleotide Metabolism in Health and Disease.
Zhao X, Zeng Y, Xu Y, Rao S, Khouchani M, Soummane H, Li J, Liu R. · 2026-08-12
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.