What it does, reaction by reaction
Fatty Acid Synthesis (De Novo Lipogenesis) Lipid Metabolism · Cytosol
Palmitoyl-ACP + H2O → palmitate + ACP
Converts Palmitoyl-ACP H2O into Palmitate ACP (acyl carrier protein)
› Notes
The thioesterase (TE) domain of FAS hydrolyzes palmitoyl-ACP, terminating synthesis predominantly at C16. This is effectively irreversible by hydrolysis, but ACC—not thioesterase—is the pathway’s principal rate-limiting step.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Nothing is fetched until you ask, so the page stays fast and the request is yours rather than automatic.
Europe PMC · ten most recent, newest first