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unreviewed

Phospholipase D

1 reactions · 1 pathways

What it does, reaction by reaction

1 reactions

Phospholipid Degradation (Phospholipases) Lipid Metabolism · Membranes, lysosome, plasma

step 4 Irreversible/directional

Phosphatidylcholine + H2O -> phosphatidic acid + choline

Converts Phosphatidylcholine H2O into Phosphatidic acid Choline

› Notes

Cleaves distal to the phosphate, releasing the head-group alcohol.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Phospholipases D: An Update on Structure-Function Relationships.

    Wu Z, Malcles L, Abousalham A, Noiriel A. · 2027-01-01

    unreviewed
  2. 2
    Phospholipases: Where Do We Stand?

    Malcles L, Wu Z, Snini S, Aloulou A, Noiriel A, Abousalham A. · 2027-01-01

    unreviewed
  3. 3
    Integrated multi-omics analysis identifies PPAR signaling network associations with metabolic-immune dysregulation and intestinal injury in PDCoV-infected piglets.

    Guo X, A C, Ding Y, Zhang Y, Zhang H, Wang J, Zhang Y, Wang T. · 2026-09-27

    open access unreviewed
  4. 4
    Codon-dependent translation of N1-ethylpseudouridine-modified mRNA reduces innate immunity while preserving vaccine immunogenicity.

    Park J, Lee G, Lee H, Kim J, Kim K, Kim E, Lee J, Lee S, Youn J, Jang YS. · 2026-09-02

    open access unreviewed
  5. 5
    Heat stress responses of plants during adaptation to high temperature environments: A review of recent advances and insights.

    Wei X, Zhang H, Ma R, Zang J, Wang Y, Yu C. · 2026-09-20

    open access unreviewed
  6. 6
    Combining a chitosan-immobilized phospholipase D with a mixed micelle system for highly efficient synthesis of phosphatidylserine.

    Liu Z, Wang C, Wu J, Chen M, Zhang Y. · 2026-08-10

    unreviewed
  7. 7
    Beyond spherical vesicles: morphological diversity of extracellular vesicles in health and disease.

    Velázquez-Cervantes MA, Fierro NA, Lozano-Hernández R, Carrero JC. · 2026-05-04

    open access unreviewed
  8. 8
    <i><b>Limosilactobacillus mucosae</b></i> <b>attenuates hyperlipidemic periodontitis via the gut-oral axis</b>.

    Xu J, Han Z, Xue Q, Wang H, Song J, Li Y, Zhang Y, Wang D, Hu M. · 2026-01-20

    cited 2× open access unreviewed
  9. 9
    Targeting CXCL8 in post-traumatic stress disorder and Alzheimer's disease: insights from cross-disorder molecular analysis.

    Liao D, Zhang M, Yang Q, Li T, Cao Z, Liu D, Zhang Z, Li X, Tian Z, Li X, Luo P. · 2026-01-09

    cited 1× open access unreviewed
  10. 10
    High-resolution Structure of the Vaccinia Virus Phospholipase D-fold Endonuclease K4.

    Gröger H, Trouba C, Barbaste J, Lacroix G, Schoehn G, Burmeister WP, Tarbouriech N. · 2026-07-29

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.