What it does, reaction by reaction
Urea Cycle Amino Acid & Nitrogen Metabolism · Mitochondrial matrix + cytosol
Carbamoyl phosphate + ornithine → citrulline + Pᵢ
Converts Carbamoyl phosphate Ornithine into Citrulline Pi
› Notes
Ornithine transcarbamylase (OTC) catalyzes this mitochondrial reaction without direct ATP use. Citrulline is exported to the cytosol in exchange for ornithine; the reaction is effectively irreversible under physiological conditions because carbamoyl phosphate is high energy.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
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1
Constipation with bloating: a clinical approach to evaluation and management.
Cangemi DJ, Laitman AP, Faiman O, Chang BW. · 2026-06-19
open access unreviewed -
2
Europium(III)-functionalized covalent organic frameworks as fluorescent switches toward ultrasensitive detection of oxytetracycline.
Ren X, Zhang W, Wang Y, Xu Y, Wang Y, Chen X. · 2026-06-15
unreviewed -
3
Advances in the application of assisted reproductive technology in fertility preservation for female patients with malignant tumours of the reproductive systems.
Sun Q, Su Y, Zhu X. · 2026-04-15
open access unreviewed -
4
Letter to the editor regarding: "influence of proton pump inhibitor use on clinical outcomes of patients with inflammatory bowel disease".
Gong Q, Jin R. · 2025-12-24
open access unreviewed -
5
Using the advantages and avoiding the risks - a public survey about the challenges of online purchases of medicines.
Persson A, Troein M, Jakobsson U, Lundin S, Midlöv P, Lenander C. · 2025-11-15
open access unreviewed -
6
Cadmium-oxytetracycline co-contamination disturbs soil ecology and triggers plant self-defense mechanisms.
Zhao W, Hu J, Lin J, Lou Y, Wang H, Yang Q, Di H, Feng H, Zhuge Y, Pan H. · 2026-06-28
unreviewed -
7
Compartmental and functional responses of the citrus microbiome and resistome to the systemic delivery of oxytetracycline by trunk injection.
Castellano-Hinojosa A, de Freitas J, de Carvalho DU, Monus BD, González-López J, Strauss SL, Albrecht U. · 2026-07-01
unreviewed -
8
Population pharmacokinetic modelling of oxytetracycline in rainbow trout (Oncorhynchus mykiss): Effects of route of administration, temperature and ploidy
Viel A, Bachelet F, Chailleux A, David C, Pineau L, Calvez S, Rostang A. · 2026-10-01
unreviewed -
9
Differential fates of antibiotics in sulfur-driven autotrophic denitrification: Ciprofloxacin transformation linked to sulfide oxidation.
Qian J, Liao X, Shi Y, Chen X. · 2026-07-29
unreviewed -
10
Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania.
Ramadhani RI, Nonga HE. · 2026-09-01
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.