What it does, reaction by reaction
Urea Cycle Amino Acid & Nitrogen Metabolism · Mitochondrial matrix + cytosol
Carbamoyl phosphate + ornithine → citrulline + Pᵢ
Converts Carbamoyl phosphate Ornithine into Citrulline Pi
› Notes
Ornithine transcarbamylase (OTC) catalyzes this mitochondrial reaction without direct ATP use. Citrulline is exported to the cytosol in exchange for ornithine; the reaction is effectively irreversible under physiological conditions because carbamoyl phosphate is high energy.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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