Nucleoside diphosphate kinases/phosphatases (NTP<->NDP pool)
What it does, reaction by reaction
Deoxyribonucleotide Formation (Ribonucleotide Reductase pathway and thymidylate synthesis) Nucleotide Metabolism · Cytosol
Ribonucleoside triphosphates → dNDP precursor pool
Converts ATP GTP CTP UTP into ADP GDP CDP UDP
› Notes
Nucleoside diphosphate phosphatases/kinases maintain interconversion between NTP and NDP pools so that ADP, GDP, CDP, and UDP are available to RNR. RNR acts on diphosphates, not directly on NTPs, a feature central to its allosteric substrate-specificity system.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Chemoproteomics identifies STAT3 as a key target of baicalin in ameliorating liver fibrosis.
Yuan S, Zhou YF, Ma B, Liu Y, Zhang J, Wang Y, Xiao W, Liu H, Wang F, Yu A, Yang W, Wang C. · 2026-02-16
open access unreviewed -
2
Nucleoside Diphosphate Kinase Family: Evolutionary Analysis and Protective Role in Mitochondrial ROS Production.
Jardim-Messeder D, de Souza-Vieira Y, Felix-Cordeiro T, Corrêa RL, Sachetto-Martins G. · 2026-04-09
open access unreviewed -
3
Dentofacial Malocclusion and Salivary Biomarkers in Asthmatic Patients: A Scoping Review.
Raghavan S, Alhaija ESA, Almashraqi AA. · 2026-02-25
open access unreviewed -
4
Proteome Analysis of Nasolacrimal Duct Lavage Fluid in Patients with Primary Acquired Nasolacrimal Duct Obstruction.
You H, Bang W, Kang B, Back S, Park J, Ju M, Park JM, Lew H. · 2026-03-12
open access unreviewed -
5
Proangiogenic Properties of Extracellular Vesicles Secreted by Endothelial Cells Reversibly Primed for Anoikis: A Possible Autocrine Mechanism Induced by Astrocytoma Extracellular Matrix.
Silva-de-Barros AOD, Alves TR, Ribeiro-Fernandes L, Helal-Neto E, Frony AC, Pontes B, Viana NB, Barreira PK, … · 2026-03-11
open access unreviewed -
6
Pharmacological evaluation of an ex vivo cervicovaginal HIV prevention model.
Collins LB, Le A, Nicol MR. · 2026-03-01
open access unreviewed -
7
Genome Imputation for Genome-Wide Association Study of Reproductive Traits in Chinese Duroc, Landrace, and Yorkshire Pigs: Strategy and Validation.
Zhou J, Fu Y, Zhang Y, Tu W, Huang J, Liang Y, Li B, Zhang H, Liu Y, Wang K, Wang H, Tan Y. · 2026-02-12
open access unreviewed -
8
Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in preclinical models of H3K27M-mutant gliomas.
Batsios G, Taglang C, Udutha S, Gillespie AM, Phoenix T, Mueller S, Venneti S, Koschmann C, Viswanath P. · 2026-02-11
cited 3× unreviewed -
9
Proteomics landscape of early T-cell precursor acute lymphoblastic leukemia reveals deficient oxidative phosphorylation signatures.
Liu M, Chen T, Lin X, Wu B, Shi F, Liu J, Chen Y, Zeng T, Hou S, Pan Q, Wang X, Yao Y, Yang W, Zhang Y, Huang… · 2026-02-03
open access unreviewed -
10
The Potential Molecular Mechanisms and Key Genes of Early Deterioration of Parenchymal Lesions in Cerebral Venous Sinus Thrombosis.
Cen G, Li J, Wang J, Chen Y, Liang Z. · 2026-01-01
unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.