unreviewed
Multiple; L-gulonolactone oxidase (GULO) is a pseudogene in primates
1 reactions · 1 pathways
Cofactors used
What it does, reaction by reaction
1 reactions
Uronic Acid Pathway Carbohydrate Metabolism · Cytosol
step 3
Irreversible/directional
UDP-glucuronate -> L-gulonate -> (L-gulonolactone) -> ascorbate
Converts UDP-glucuronate into L-Gulonate
› Notes
Humans, other primates and guinea pigs lack functional GULO, so ascorbate is a dietary vitamin rather than a metabolic product.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
0 entries
No regulation recorded for this enzyme in the source documents.
Recent literature
No articles returned.