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unreviewed

Guanine deaminase (guanase)

1 reactions · 1 pathways

Cofactors used

H2O

What it does, reaction by reaction

1 reactions

Purine Degradation (to Uric Acid) Nucleotide Metabolism · Cytosol

step 10 Irreversible/directional

Guanine → xanthine

Converts Guanine into Xanthine

› Notes

Guanine deaminase (guanase) catalyzes guanine + H2O → xanthine + NH3. Xanthine then enters step 7 and is oxidized to uric acid.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

0 entries

No regulation recorded for this enzyme in the source documents.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Phenotypic profiling of neutrophils in acute <i>Clostridioides difficile</i> infection identifies a TNF-induced activation signature associated with epithelial damage.

    Huber A, Mathew A, Khondokar F, Sharma D, Mukherjee A, Khona DK, Gabriel J, Jose S, Madan R. · 2026-04-23

    open access unreviewed
  2. 2
    Hsa_circ_0000711 can serve as a novel biomarker for primary biliary cholangitis by promoting disease progression through the regulation of miR-185-5p and NFATc3.

    Lu W, Li W, Wang P, Cong P, Wang Z, Gao W, Sun G, Liu M. · 2026-03-25

    open access unreviewed
  3. 3
    <i>Fusobacterium nucleatum</i> plays a pathogenic role in a murine model of irritable bowel syndrome by modulating intestinal purine metabolism and promoting mast cell activation.

    Hou S, Ning T, Liu S, Yang X, Ye H, Zhou Y, Wang C, Zhu J, Lu S, Zhang N, Zhu S. · 2026-01-28

    open access unreviewed
  4. 4
    Integrating aptamer-transduced signal amplification and superwettable droplet microarrays for single-cell detection of cell surface vimentin.

    Miao X, Lang G, Xiao X, Yang S, Zhao J, Zhou M, Wang X, Zaczek A, Liu J. · 2026-04-21

    unreviewed
  5. 5
    Drug-natural molecule coupling as a rational strategy in the development of an innovative antiparasitic, anti-inflammatory and cardioprotective drug for Chagas disease treatment.

    Benedetti MD, Pelozo MF, Souza E Leite EG, Camargo TP, Castro LFD, Lima GDA, Caldas S, Hawkes JA, Gonçalves R… · 2026-07-05

    unreviewed
  6. 6
    Association between automated brain volumetry and visual classification of hippocampal atrophy in MRI.

    Garrafiel FN, Soder RB, Paganin RP, da Silva MRA, Bieger A, Vidaletti VV, Lazzareti FJ, Zimmer ER, da Costa J… · 2026-06-14

    open access unreviewed
  7. 7
    DNA detection of Babesia bovis in sheep, ticks and cattle during an outbreak of sheep ixodidiosis by Rhipicephalus microplus.

    Lima Neto BF, Batista SP, Alvares FBV, Monteiro YS, Silva MLP, Martins HEC, Silva WI, Medeiros GDA, Feitosa T… · 2026-08-07

    unreviewed
  8. 8
    Semi-inlay and onlay humeral stems in reverse shoulder arthroplasty achieve comparable outcomes through different patterns of glenoid and humeral lateralization and distalization: A retrospective study from the FP-UCBM Shoulder Study Group.

    Paciotti M, De Rosa A, Franceschetti E, La Bruna M, Gregori P, Ciuffreda M, Perricone G, Giurazza G, Papalia … · 2026-08-03

    unreviewed
  9. 9
    Evaluating the Quality and Impact of Online Patient Forums in Genomic Data Governance.

    Eric A, Christoph S, Züger A, Winkler EC, Katja M. · 2026-08-01

    unreviewed
  10. 10
    [Safety and efficacy of bovine pericardial patch wrapping of the hepatic artery for preventing delayed postpancreatectomy hemorrhage after laparoscopic pancreaticoduodenectomy].

    Hu AZ, Wang J, Ma HQ, Liu L, Du YS, Tang HD, Zhao WX. · 2026-08-01

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.