Glycogen debranching enzyme (AGL) - 4-alpha-glucanotransferase activity
Clinical / pharmacological. Cori-Forbes disease (GSD III)
What it does, reaction by reaction
Glycogenolysis (Glycogen Breakdown) Carbohydrate Metabolism · Cytosol + ER (liver)
Limit dextrin: transfer of a three-residue alpha(1→4)-linked segment to a neighboring nonreducing end
Converts Glycogen limit dextrin into Glycogen limit dextrin (transferred branch)
› Notes
The 4-alpha-glucanotransferase activity of the bifunctional glycogen debranching enzyme moves a block of three glucosyl residues from the short branch to another alpha(1→4) chain. No nucleotide cofactor is required.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
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