What it does, reaction by reaction
Sphingolipid Synthesis Lipid Metabolism · ER + Golgi
Ceramide + UDP-glucose -> glucosylceramide + UDP
Converts Ceramide UDP-glucose into Glucosylceramide UDP
› Notes
Entry to the glycosphingolipid/ganglioside series; sequential glycosyltransferases then build lactosylceramide, globosides and gangliosides.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
No regulation recorded for this enzyme in the source documents.
Recent literature
Europe PMC · fetched just now · sorted by publication date
-
1
BmK IT2 suppresses proliferation while differentially modulates migration and invasion of neural tumor cells: Association with down-regulation of functional VGSCs and transcriptional reprogramming.
Jing S, Wang J, Cheng S, Ma Q, Tao J, Wang H, Ji Y, Tan Z, Zhou Y. · 2026-05-25
unreviewed -
2
Glycosphingolipids are essential entry factors for non-influenza orthomyxoviruses.
Lozano-Montalbá L, Denis Z, Courgnaud V, Moreno-García J, Majzoub K, Sanjuán R, Dufloo J. · 2026-08-01
unreviewed -
3
Extracellular vesicle depletion improves transient gene expression performance and alters cellular transcriptional responses in CHO cell.
Rahimi M, Pérez-Rubio P, Vargas-Gracia J, Kempen PJ, Nielsen LK, Lavado-García J. · 2026-07-07
unreviewed -
4
Integrative multi‑omics analysis of lipid metabolism during the growth and development of Qiandongnan Xiaoxiang chickens based on the gut‑muscle axis.
Xie Y, Yi L, Cheng W, Jia H, Zhang W, Song G, Zhu J, Zhao S. · 2026-04-23
open access unreviewed -
5
Molecular mechanisms of neuroendocrine regulation of molting in the Chinese mitten crab (Eriocheir sinensis): A transcriptomic analysis based on eyestalk ablation model.
Fu C, Fu X, Li Z, Li F, Wang L, Dong Y. · 2026-07-30
unreviewed -
6
An ABC-B Transporter Helps Protect <i>Fusarium graminearum</i> Against Enniatin Toxicity.
Harris LJ, Bosnich W, Johnston A, Schneiderman D, Kwan R, Thapa I, Witte TE, Sproule A, Gleddie S, Blackwell … · 2026-07-17
unreviewed -
7
Integrated Multi-omics Analysis Uncovers Molecular Dysregulation in Glycosylceramide Synthase-Deficient Human Induced Pluripotent Stem Cells.
Beimdiek J, Cirksena K, Rossdam C, Brand-Merseburger S, Oberbeck A, Barbosa PV, Tzvetkova A, Juchem M, Bär C,… · 2026-07-23
unreviewed -
8
Single-cell RNA sequencing reveals lipid metabolism disorders in the retina in spontaneous high myopia.
Bao B, Liu J, Xie Y, Xi R, Sun Y, Yan J, Xin J, Yang Z, Yin X, Guo D, Bi H. · 2026-07-02
unreviewed -
9
Assessing Surface Binding Events on Golgi Microsomes Isolated from Cancer Cells by Capillary Electrophoresis.
Davoine C, Cobraiville G, Pochet L, Fillet M. · 2026-06-24
unreviewed - 10
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.