Galactokinase (GALK1)
Cofactors used
Clinical / pharmacological. Galactokinase deficiency: isolated cataracts
What it does, reaction by reaction
Galactose Metabolism Carbohydrate Metabolism · Cytosol
Galactose + ATP → galactose-1-phosphate + ADP
Converts Galactose ATP into Galactose-1-phosphate ADP
› Notes
Galactokinase (GALK1) requires ATP and Mg2+ and phosphorylates galactose at carbon 1. This is effectively irreversible and traps galactose intracellularly.
Showing all 1 reactions.
What accelerates and inhibits it
Regulation is pathway-specific, so each context is listed separately
Galactose Metabolism
Listed there as: Galactokinase
Galactose availability
No established major physiological allosteric inhibitor
No major acute hormonal control
Recent literature
Europe PMC · from cache · sorted by publication date
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1
Enhanced lactose utilization from milk enriched in Uridine-5'-monophosphate drives hepatic energy storage in young mammals.
Gao LM, Liu L, Yang XD, Long CM, Wu X. · 2026-06-01
open access unreviewed -
2
Meta-analyses of genome-wide association studies identify novel loci influencing Japanese white matter hyperintensities.
Asanomi Y, Mitsumori R, Yamakawa A, Morizono T, Shigemizu D, Niida S, Sakurai T, Ozaki K. · 2026-01-20
open access unreviewed -
3
Elucidating the therapeutic targets and multi-target mechanisms of salvianolic acid A for diabetic nephropathy.
Fu T, Xiong Z, Tao H, Zhan Y. · 2026-06-24
unreviewed -
4
Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients.
Liutkute A, Berrandou TE, Kestel S, Schnelle M, Dschun O, Amedei HA, Neuenroth L, Rytkin E, Kyshynska O, Kens… · 2026-06-01
cited 2× open access unreviewed -
5
30-hydroxygambogic acid activates overlapping and independent apoptotic pathways in HPV positive and HPV negative oral cancer cells.
Grubbs D, Whang S, Rodarte V, Martinez B, Filippov V, Chen J, Coats J, Unternaehrer J, Kremsky I, Vazquez B, … · 2026-02-08
open access unreviewed -
6
Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids.
Gaston-Breton R, Bouzid A, Antipushina E, Costa N, Sarkadi B, Apati A, Harati R, Sharaev M, Armengaud J, Disd… · 2026-04-11
open access unreviewed -
7
Ion-Channel-Mediated Drug Repurposing Opportunities Validated by Single-Cell Perturbation in Colorectal Cancer.
Dong Z, Meng X, Wang L. · 2026-04-10
open access unreviewed -
8
Multienzyme Platform for the Synthesis of UDP Sugars and Human Milk Oligosaccharides.
Hoang TS, Lange F, Kleeberg SB, Thomas L, Hoang NH, Reichl U, Rexer TFT. · 2026-04-01
open access unreviewed -
9
Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker.
Li H, Liu S, Miao D, Chen L, Sun Y, Wang G, Zhu Z, Li X, Lu Q. · 2026-03-26
open access unreviewed -
10
Iturin derived from <i>Bacillus</i> modulates lipid and glucose metabolism while mitigating the progression of MASLD.
Zhao L, Liu Q, He J, Li Y, Zhang Y, Feng Y, Zhao W, Zhang L, Liu Y, Li T, Liu H. · 2026-03-25
open access unreviewed
External claims. These come from an index outside this database and are not checked against it. Treat them as leads.