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unreviewed

Galactokinase (GALK1)

1 reactions · 1 pathways

Cofactors used

ATP Mg2+ · Magnesium

Clinical / pharmacological. Galactokinase deficiency: isolated cataracts

What it does, reaction by reaction

1 reactions

Galactose Metabolism Carbohydrate Metabolism · Cytosol

step 3 Irreversible

Galactose + ATP → galactose-1-phosphate + ADP

Converts Galactose ATP into Galactose-1-phosphate ADP

› Notes

Galactokinase (GALK1) requires ATP and Mg2+ and phosphorylates galactose at carbon 1. This is effectively irreversible and traps galactose intracellularly.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Galactose Metabolism

Listed there as: Galactokinase

Accelerated by

Galactose availability

Inhibited by

No established major physiological allosteric inhibitor

Hormonal control

No major acute hormonal control

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Enhanced lactose utilization from milk enriched in Uridine-5'-monophosphate drives hepatic energy storage in young mammals.

    Gao LM, Liu L, Yang XD, Long CM, Wu X. · 2026-06-01

    open access unreviewed
  2. 2
    Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase.

    Ko CW, Shin D, Park J, Huh J, Kim Y, Park JW. · 2026-09-30

    open access unreviewed
  3. 3
    Cell culture medium influences RSV G protein glycosylation and recognition by monoclonal antibodies.

    Engling N, Knittler MC, Tagore R, Ludlow M, Osterhaus ADME, Rimmelzwaan GF, Meineke R. · 2026-09-29

    open access unreviewed
  4. 4
    Parvovirus B19 and Cellular Transcriptome Dynamics in UT7/EpoS1 Cells.

    Guglietta N, Bichicchi F, Gasperini I, Manaresi E, Gallinella G. · 2026-09-08

    open access unreviewed
  5. 5
    Conjugated Linoleic Acid Alleviates Hepatic Steatosis and Liver Damage in Estradiol-Induced FLHS Roosters by Reshaping Lipid Metabolism and Inhibiting the MAPK/NF-κB-Mediated Inflammation Cascade.

    Liu X, Zhang H, Gao Q, Shang Y, Shi T, Yan P, Fu C. · 2026-09-03

    open access unreviewed
  6. 6
    Hereditary Congenital Cataract With Spastic Paraplegia Associated With a Missense PAX6 Variant (p.Arg26Trp).

    Miura S, Namiguchi K, Matsumoto S, Sun Y, Shibata H. · 2026-08-25

    open access unreviewed
  7. 7
    Proteome of Human Scalp Hair Follicles.

    Hegde A, Srinivasan Y, Chavan MA, Kalsi G. · 2026-08-24

    open access unreviewed
  8. 8
    Development and internal validation of a six-gene prognostic model based on galactose metabolism for overall survival in lung adenocarcinoma.

    Zhang F, Fu J, Cui X, Gao X, Kang Y. · 2026-08-27

    open access unreviewed
  9. 9
    Phytochemical Profiling and Proteomic Insights into the Anti-Inflammatory Effects of Jing Guan Fang in LPS-Stimulated Macrophages.

    Yeon S, Alsherbiny MA, Sun YT, Low MN, Li CG. · 2026-08-13

    open access unreviewed
  10. 10
    The Spanish Uniform Newborn Screening Panel (SUSP): A National Consensus Framework for Harmonized Newborn Screening.

    García-Villoria J, López-Galera RM, Delgado-Pecellín C, Rausell Félix D, Colón C, Rocha H, Pérez B, Ribes A, … · 2026-08-13

    open access unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.