unreviewed

Galactokinase (GALK1)

1 reactions · 1 pathways

Cofactors used

ATP Mg2+ · Magnesium

Clinical / pharmacological. Galactokinase deficiency: isolated cataracts

What it does, reaction by reaction

1 reactions

Galactose Metabolism Carbohydrate Metabolism · Cytosol

step 3 Irreversible

Galactose + ATP → galactose-1-phosphate + ADP

Converts Galactose ATP into Galactose-1-phosphate ADP

› Notes

Galactokinase (GALK1) requires ATP and Mg2+ and phosphorylates galactose at carbon 1. This is effectively irreversible and traps galactose intracellularly.

Showing all 1 reactions.

What accelerates and inhibits it

Regulation is pathway-specific, so each context is listed separately

1 entries

Galactose Metabolism

Listed there as: Galactokinase

Accelerated by

Galactose availability

Inhibited by

No established major physiological allosteric inhibitor

Hormonal control

No major acute hormonal control

Recent literature

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