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G6PD XR unreviewed

G6PD deficiency

Pentose Phosphate Pathway (Oxidative and Non-oxidative phases) Glucose-6-phosphate dehydrogenase

Enzyme or protein defect

Glucose-6-phosphate dehydrogenase

Accumulates or becomes deficient

Low NADPH and GSH

Key features

Episodic haemolysis with oxidants (primaquine, sulfonamides, nitrofurantoin, dapsone, fava beans, infection); Heinz bodies, bite cells

Management

Avoid oxidant triggers

Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.

Recent literature

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Europe PMC · fetched just now · sorted by publication date

  1. 1
    Neonatal genetic sequencing as a first-tier option: a real-world clinical implementation study in Northern China.

    Mu J, Sun M, Li Y, Li P, Zou H. · 2026-07-09

    open access unreviewed
  2. 2
    Vaccination practice and safety in children with special health care needs: A retrospective study of 1278 children.

    Song Y, Sun J, Ling Y, Liu S, Xu Z, Ma M, Zhang O, Zhao X. · 2026-07-06

    open access unreviewed
  3. 3
    Ultrasound-guided injection strategies for lateral epicondylitis: a multicenter randomized comparison of corticosteroid, platelet-rich plasma, and ozone.

    Raeissadat SA, Khavari Ardestani D, Mousavikhah SE, Bayat M, Babaee M, PourAzin M. · 2026-04-13

    cited 2× open access unreviewed
  4. 4
    Association between maternal stress hormone levels during labor induction and the occurrence of neonatal hyperbilirubinemia.

    Liu S, Xiao H, Wang Y, Liu H, Qi X, Fang Y, Zhang L. · 2026-02-02

    unreviewed
  5. 5
    Thiamin deficiency in children with chronic kidney disease on peritoneal dialysis and its association with dialysis duration and transport peritoneal membrane status.

    Suwanboriboon W, Chaiyapuk T, Tinnabut I, Sanpawitayakul G, Srisawat C, Junnu S, Liammongkolkul S, Chotipanan… · 2025-06-23

    cited 2× open access unreviewed
  6. 6
    A systematic review and individual patient data meta-analysis to determine the effect of primaquine dose on efficacy, tolerability and safety in uncomplicated <i>Plasmodium vivax</i> malaria in Latin America.

    Nguyen K, de Pina-Costa A, Rajasekhar M, Chamma-Siqueira NN, Daher A, Ferreira MU, Gomes MDSM, Gonzalez-Ceron… · 2026-09-12

    open access unreviewed
  7. 7
    Structural and functional effects of carbonylation and phosphorylation on the Zu5-ANK domain: A molecular dynamics and docking study.

    De La Rosa Cogollo I, Flórez-Valiente A, Cabarcas-Herrera C, Pérez-González H, Rodríguez-Cavallo E, Méndez-Cu… · 2026-07-24

    unreviewed
  8. 8
    Systematic Review and Meta-analysis on the Prevalence of Common Hemoglobinopathies in India.

    Das S, Ghai G, Sathianath S, Savitha S, Sumathi S, Joseph FK, Satapathy P, Gandhi AP. · 2026-04-06

    open access unreviewed
  9. 9
    Community-Centric Malaria Prevention in Sub-Saharan Africa: A Narrative Review of Pathways to Elimination and Global Health Impact.

    Obeagu EI. · 2026-09-28

    open access unreviewed
  10. 10
    International experiences of genomic newborn screening: Lessons from over 10,800 newborns.

    Stark Z, Lunke S, Boemer F, Cope HL, Scharfe C, Servais L, Chung WK. · 2026-09-21

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.