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G6PD XR unreviewed

G6PD deficiency

Pentose Phosphate Pathway (Oxidative and Non-oxidative phases) Glucose-6-phosphate dehydrogenase

Enzyme or protein defect

Glucose-6-phosphate dehydrogenase

Accumulates or becomes deficient

Low NADPH and GSH

Key features

Episodic haemolysis with oxidants (primaquine, sulfonamides, nitrofurantoin, dapsone, fava beans, infection); Heinz bodies, bite cells

Management

Avoid oxidant triggers

Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.

Recent literature

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Europe PMC · from cache · sorted by publication date

  1. 1
    Ultrasound-guided injection strategies for lateral epicondylitis: a multicenter randomized comparison of corticosteroid, platelet-rich plasma, and ozone.

    Raeissadat SA, Khavari Ardestani D, Mousavikhah SE, Bayat M, Babaee M, PourAzin M. · 2026-04-13

    open access unreviewed
  2. 2
    Association between maternal stress hormone levels during labor induction and the occurrence of neonatal hyperbilirubinemia.

    Liu S, Xiao H, Wang Y, Liu H, Qi X, Fang Y, Zhang L. · 2026-02-02

    unreviewed
  3. 3
    Thiamin deficiency in children with chronic kidney disease on peritoneal dialysis and its association with dialysis duration and transport peritoneal membrane status.

    Suwanboriboon W, Chaiyapuk T, Tinnabut I, Sanpawitayakul G, Srisawat C, Junnu S, Liammongkolkul S, Chotipanan… · 2025-06-23

    cited 2× open access unreviewed
  4. 4
    Combined Red Cell Exchange and Plasma Exchange for Post-Arrest Refractory Cardiorespiratory Failure in Sickle Cell Disease Sparing Extracorporeal Membrane Oxygenation.

    Attia AE. · 2026-07-28

    unreviewed
  5. 5
    NO modulates human airway smooth muscle function by altering glucose-6-phosphate dehydrogenase effects on sGC function in asthma.

    Ghosh A, Sumi MP, Koziol-White C, Tupta B, Wang L, Ghosh C, Jester WF, Panettieri RA, Stuehr DJ. · 2026-06-15

    unreviewed
  6. 6
    Discordantly low HbA1c revealing undiagnosed G6PD deficiency in a patient with type 2 diabetes mellitus.

    Tay WL, Chay JWM, Hawkins RCW, Li BV, Lum MYJ, Ho CKM. · 2026-03-19

    unreviewed
  7. 7
    Predictive value of the 24-hour bilirubin in the development of significant hyperbilirubinemia among Filipino term (≥37 weeks gestational age) infants: a prospective multi-center study.

    Philippine society of newborn medicine Bilistick study group. · 2026-08-06

    unreviewed
  8. 8
    Cognitive Decline, Neurologic Involvement, and Neonatal Crisis in <i>ABCC9</i>-Related Intellectual Disability and Myopathy Syndrome.

    Nagaraj V, Thomas QH, Nóbrega PR, Rodriguez Gil JL, Garavatti E, Scala M, Severino M, Efthymiou S, Amaral S, … · 2026-06-10

    open access unreviewed
  9. 9
    Efficacy of delayed tafenoquine administration for radical cure of Plasmodium vivax Malaria: A systematic review.

    DeVita TN, Hwang J, Gutman JR, Ridpath AD, Williams S, Chang MA. · 2026-06-06

    unreviewed
  10. 10
    Glucose-6-phosphate dehydrogenase activity and genetic variants in tunisian diabetic populations: A case-control study.

    Amri Y, Othmani M, Hannachi N, Tombari S, Chelbi S, Dridi A, Zmerli N, Hadj Fredj S, Messaoud T, Dabboubi R. · 2026-05-14

    unreviewed

External claims. These come from an index outside this database and are not checked against it. Treat them as leads.