G6PD XR unreviewed
G6PD deficiency
Enzyme or protein defect
Glucose-6-phosphate dehydrogenase
Accumulates or becomes deficient
Low NADPH and GSH
Key features
Episodic haemolysis with oxidants (primaquine, sulfonamides, nitrofurantoin, dapsone, fava beans, infection); Heinz bodies, bite cells
Management
Avoid oxidant triggers
Not clinical guidance. Written from standard clinical biochemistry, not from the uploaded documents, and marked unreviewed. Teaching-level reference for study and database seeding only. It must not be used to manage a patient.
Recent literature
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